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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang
收藏  |  浏览/下载:63/0  |  提交时间:2022/01/18
Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12050202] 项目
项目编号: XDA12050202, 资助机构: Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences, 2021-
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收藏  |  浏览/下载:165/0  |  提交时间:2021/05/24
Accucopy: accurate and fast inference of allele-specific copy number alterations from low-coverage low-purity tumor sequencing data 期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 1, 页码: 18
作者:  Fan, Xinping;  Luo, Guanghao;  Huang, Yu S.
收藏  |  浏览/下载:217/0  |  提交时间:2021/05/24
Personalized Medicines-Molecular Signature-based Drug Discovery and Development, Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12020229] 项目
项目编号: XDA12020229, 资助机构: Personalized Medicines-Molecular Signature-based Drug Discovery and Development, Strategic Priority Research Program of the Chinese Academy of Sciences, 2021-
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收藏  |  浏览/下载:2/0  |  提交时间:2022/01/18
GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Zhang, Qing;  Chen, Lin-hai;  Yang, Hui;  Fang, You-chen;  Wang, Si-wei
收藏  |  浏览/下载:47/0  |  提交时间:2022/01/18
Strategic Priority Research Program of Chinese Academy of Sciences[XDA12040204] 项目
项目编号: XDA12040204, 资助机构: Strategic Priority Research Program of Chinese Academy of Sciences, 2021-
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收藏  |  浏览/下载:2/0  |  提交时间:2022/01/18
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo
收藏  |  浏览/下载:44/0  |  提交时间:2022/01/18
New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Yong-Mei;  Ye, Lu-Yu;  Li, Tian-Yu;  Guo, Fan;  Guo, Fei
收藏  |  浏览/下载:23/0  |  提交时间:2022/01/04
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:  He, Yu-Long;  Chen, Meng-Ting;  Wang, Ting;  Zhang, Ming-Ming;  Li, Ying-Xia
收藏  |  浏览/下载:66/0  |  提交时间:2021/11/04
SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade 期刊论文
EMBO JOURNAL, 2021, 页码: 16
作者:  Wang, Xu;  Ni, Jiahui;  You, Yan;  Feng, Guize;  Zhang, Sulin
收藏  |  浏览/下载:38/0  |  提交时间:2021/12/16


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