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浏览/检索结果: 共5条，第1-5条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions 期刊论文 DRUG METABOLISM AND DISPOSITION, 2015, 卷号: 43, 期号: 5, 页码: 669-678 作者:  Jia, Weiwei;  Du, Feifei;  Liu, Xinwei;  Jiang, Rongrong;  Xu, Fang 收藏  |  浏览/下载：40/0  |  提交时间：2019/01/08 Effects of Renal Impairment on the Pharmacokinetics of Morinidazole: Uptake Transporter-Mediated Renal Clearance of the Conjugated Metabolites 期刊论文 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 卷号: 58, 期号: 7, 页码: 4153-4161 作者:  Zhong, Kan;  Li, Xiuli;  Xie, Cen;  Zhang, Yifan;  Zhong, Dafang 收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 A chiral high-performance liquid chromatography-tandem mass spectrometry method for the stereospecific determination of morinidazole in human plasma 期刊论文 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2014, 卷号: 961, 页码: 49-55 作者:  Zhong, Kan;  Gao, Zhiwei;  Li, Qin;  Zhong, Dafang;  Chen, Xiaoyan 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Morinidazole enantiomer  Liquid chromatography-tandem mass spectrometry  Stereoselective pharmacokinetics  5-Nitroimidazole antimicrobial drug   EFFECT OF RENAL IMPAIRMENT ON THE PHARMACOKINETICS OF MORINIDAZOLE: ALTERED UPTAKE TRANSPORTER-MEDIATED RENAL CLEARANCE? 会议论文 作者:  Chen, Xiaoyan;  Xie, Cen;  Zhong, Kong;  Li, Xiuli;  Zhong, Dafang 收藏  |  浏览/下载：8/0  |  提交时间：2019/01/08 Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling 期刊论文 ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 11, 页码: 1359 作者:  Li Guofu;  Wang Kun;  Chen Rui;  Zhao Haoru;  Yang Jin 收藏  |  浏览/下载：9/0  |  提交时间：2020/12/24 TISSUE DISTRIBUTION  DRUG DISCOVERY  INTRASUBJECT VARIABILITY  PBPK SIMULATION  P-GP  ABSORPTION  POPULATION  PREDICTION  BIOAVAILABILITY  IDENTIFICATION  bisoprolol  whole-body physiologically based pharmacokinetic model  drug absorption  drug distribution  renal function impairment