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CORC

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Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14
作者:  Zhang, Chun;  Sun, Yi-Tao;  Gao, Li-Xin;  Feng, Bo;  Yan, Xue
收藏  |  浏览/下载：22/0  |  提交时间：2022/01/18
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun
收藏  |  浏览/下载：32/0  |  提交时间：2021/12/01
Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1) 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105
作者:  Yu Lijie;  Feng Bo;  Wang Zhijia;  Gao Lixin;  Zhang Chun
收藏  |  浏览/下载：243/0  |  提交时间：2021/11/04
Transcriptome Regulation by Oncogenic ALK Pathway in Mammalian Cortical Development Revealed by Single-Cell RNA Sequencing 期刊论文
CEREBRAL CORTEX, 2021, 卷号: 31, 期号: 8, 页码: 3911-3924
作者:  Mao, Rui;  Zhang, Xiaoyun;  Kong, Youyong;  Wu, Shanshan;  Huo, Hai-qin
收藏  |  浏览/下载：35/0  |  提交时间：2021/08/17
The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability 期刊论文
MOLECULAR CELL, 2021, 卷号: 81, 期号: 13, 页码: 2736-+
作者:  Pan, Qiang;  Zhong, Shanshan;  Wang, Hanling;  Wang, Xuege;  Li, Ni
收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei
收藏  |  浏览/下载：41/0  |  提交时间：2021/08/17
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:  Gao, Dingding;  Jin, Nan;  Fu, Yixian;  Zhu, Yueyue;  Wang, Yujie
收藏  |  浏览/下载：43/0  |  提交时间：2021/06/11
Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 7, 页码: 3956-3975
作者:  Zhang, Hefeng;  Peng, Xia;  Dai, Yang;  Shao, Jingwei;  Ji, Yinchun
收藏  |  浏览/下载：17/0  |  提交时间：2021/06/11
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 18
作者:  Bernasocchi, Tiziano;  El Tekle, Geniver;  Bolis, Marco;  Mutti, Azzurra;  Vallerga, Arianna
收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24

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