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CORC

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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang
收藏  |  浏览/下载：63/0  |  提交时间：2022/01/18
Structurally diverse diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debx. and their anti-tumor activities based on in vitro systematic evaluation and network pharmacology analysis 期刊论文
RSC ADVANCES, 2021, 卷号: 11, 期号: 43, 页码: 26594-26606
作者:  Yu, Yang;  Wu, Shifei;  Zhang, Jianqing;  Li, Jiayuan;  Yao, Changliang
收藏  |  浏览/下载：29/0  |  提交时间：2021/11/04
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells 期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:  Zhang, Mi;  Quan, Haitian;  Fu, Li;  Li, Yun;  Fu, Haoyu
收藏  |  浏览/下载：19/0  |  提交时间：2021/05/24
Deformable liposomal codelivery of vorinostat and simvastatin promotes antitumor responses through remodeling tumor microenvironment 期刊论文
BIOMATERIALS SCIENCE, 2020, 卷号: 8, 期号: 24, 页码: 7166-7176
作者:  Tu, Bin;  He, Yang;  Chen, Binfan;  Wang, Yonghui;  Gao, Yanrong
收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24
Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2020, 卷号: 19, 期号: 11, 页码: 2340-2352
作者:  Jin, Rui;  Liu, Liang;  Xing, Yun;  Meng, Tao;  Ma, Lanping
收藏  |  浏览/下载：52/0  |  提交时间：2020/12/24
An antibody-drug conjugate targeting a GSTA glycosite-signature epitope of MUC1 expressed by non-small cell lung cancer 期刊论文
CANCER MEDICINE, 2020, 页码: 12
作者:  Pan, Deng;  Tang, Yubo;  Tong, Jiao;  Xie, Chengmei;  Chen, Jiaxi
收藏  |  浏览/下载：21/0  |  提交时间：2020/12/24
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant 期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:  Hu, Xianglong;  Xun, Qiuju
收藏  |  浏览/下载：48/0  |  提交时间：2020/07/01
Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells (vol 37, pg 1587, 2020) 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 2
作者:  Wang, Yue-qin;  Shen, Ai-jun;  Sun, Jing-ya;  Wang, Xin;  Liu, Hong-chun
收藏  |  浏览/下载：12/0  |  提交时间：2020/07/01
Inhibition of Tumor Lymphangiogenesis is an Important Part that EGFR-TKIs Play in the Treatment of NSCLC 期刊论文
JOURNAL OF CANCER, 2020, 卷号: 11, 期号: 1, 页码: 241-250
作者:  Zhang, Yan;  Yang, Xinying;  Liu, Hongchun;  Cai, Minghui;  Yang Shentu
收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01

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