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Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 7, 页码: 1885-1902
作者:  Wu, Xu;  Yin, Chun;  Ma, Jiang;  Chai, Stella;  Zhang, Chunyuan
收藏  |  浏览/下载:39/0  |  提交时间:2021/11/04
Dihydro-beta-agarofuran-Type Sesquiterpenoids from the Seeds of Celastrus virens and Their Multidrug Resistance Reversal Activity against the KB/VCR Cell Line 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 3, 页码: 588-600
作者:  Mu, Hongyan;  Tang, Shuai;  Zuo, Quan;  Huang, Min;  Zhao, Weimin
收藏  |  浏览/下载:33/0  |  提交时间:2021/05/24
A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 8
作者:  Chen, Lu;  Quan, Haitian;  Xu, Zhongliang;  Wang, Hao;  Xia, Yuanzhi
收藏  |  浏览/下载:18/0  |  提交时间:2020/12/24
Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling 期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305
作者:  Chen, Jianzhong;  Peng, Cheng;  Wang, Jinan;  Zhu, Weiliang
收藏  |  浏览/下载:59/0  |  提交时间:2019/01/08
A 20(S)-protopanaxadiol derivative PPD12 reverses ABCB1-mediated multidrug resistance with oral bioavailability and low toxicity 期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 16, 期号: 5, 页码: 5891-5899
作者:  Wei, Shunfeng;  Chen, Wantao;  Hu, Lihong;  Pan, Jinsong;  Wang, Xu
收藏  |  浏览/下载:85/0  |  提交时间:2019/01/08
New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264
作者:  Tian, Qian-Ting;  Ding, Chun-Yong;  Song, Shan-Shan;  Wang, Ying-Qing;  Zhang, Ao
收藏  |  浏览/下载:42/0  |  提交时间:2019/01/08
Jatrophanes as promising multidrug resistance modulators: Advances of structure-activity relationships 期刊论文
FITOTERAPIA, 2018, 卷号: 127, 页码: 138-145
作者:  Li, Jun;  Wang, Wen-qiong;  Tang, Shuai;  Song, Wei-bin;  Xuan, Li-jiang
收藏  |  浏览/下载:50/0  |  提交时间:2019/01/08
Novel Nitric Oxide Donors of Phenylsulfonylfuroxan and 3-Benzyl Coumarin Derivatives as Potent Antitumor Agents 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 5, 页码: 502-506
作者:  Guo, Yalan;  Wang, Yujie;  Li, Haihong;  Wang, Ke;  Wan, Qi
收藏  |  浏览/下载:31/0  |  提交时间:2019/01/08
Resin glycosides from the seeds of Ipomoea muricata and their multidrug resistance reversal activities 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 149, 页码: 24-30
作者:  Wang, Wen-qiong;  Liu, Shan-shan;  Song, Wei-bin;  Li, Jun;  Xuan, Li-jiang
收藏  |  浏览/下载:25/0  |  提交时间:2019/01/08
ES2 enhances the efficacy of chemotherapeutic agents in ABCB1-overexpressing cancer cells in vitro and in vivo 期刊论文
PHARMACOLOGICAL RESEARCH, 2018, 卷号: 129, 页码: 388-399
作者:  Fang, Yanfen;  Sun, Juanjuan;  Zhong, Xing;  Hu, Rui;  Gao, Jie
收藏  |  浏览/下载:36/0  |  提交时间:2019/01/08


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