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CORC

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Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载：24/0  |  提交时间：2022/01/04
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng
收藏  |  浏览/下载：97/0  |  提交时间：2021/11/04
A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-κB pathway 期刊论文
Cancer Cell International, 2021, 卷号: 21, 期号: 1
作者:  Gao,Xuejie;  Li,Bo;  Ye,Anqi;  Wang,Houcai;  Xie,Yongsheng
收藏  |  浏览/下载：98/0  |  提交时间：2021/06/11
A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-kappa B pathway 期刊论文
CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 10
作者:  Gao, Xuejie;  Li, Bo;  Ye, Anqi;  Wang, Houcai;  Xie, Yongsheng
收藏  |  浏览/下载：22/0  |  提交时间：2021/08/17
Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers 期刊论文
INVESTIGATIONAL NEW DRUGS, 2021, 页码: 9
作者:  Li, Meng-Zhu;  Meng, Tao;  Song, Shan-Shan;  Bao, Xu-Bin;  Ma, Lan-Ping
收藏  |  浏览/下载：69/0  |  提交时间：2021/05/24
Inhibition of B-cell receptor signaling disrupts cell adhesion in mantle cell lymphoma via RAC2 期刊论文
BLOOD ADVANCES, 2021, 卷号: 5, 期号: 1, 页码: 185-197
作者:  Wu, Wenjun
收藏  |  浏览/下载：49/0  |  提交时间：2020/07/01
Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2020, 卷号: 46, 期号: 6, 页码: 2137-2149
作者:  Pan, Lijia;  Nie, Litong;  Yao, Sheng;  Bi, Aiwei;  Ye, Yang
收藏  |  浏览/下载：30/0  |  提交时间：2020/12/24
An antibody-drug conjugate targeting a GSTA glycosite-signature epitope of MUC1 expressed by non-small cell lung cancer 期刊论文
CANCER MEDICINE, 2020, 页码: 12
作者:  Pan, Deng;  Tang, Yubo;  Tong, Jiao;  Xie, Chengmei;  Chen, Jiaxi
收藏  |  浏览/下载：21/0  |  提交时间：2020/12/24
Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment 期刊论文
SCIENCE ADVANCES, 2020, 卷号: 6, 期号: 18, 页码: 11
作者:  Wang, Leiming;  Cheng, Chiang-Min;  Qin, Jun;  Xu, Mafei;  Kao, Chung-Yang
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01

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