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Recent Progress and Clinical Development of Inhibitors that Block MDM4/p53 Protein-Protein Interactions 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 10621-10640
作者:  Zhang, Shiyan;  Lou, Jianfeng;  Li, Yafang;  Zhou, Feilong;  Yan, Ziqin
收藏  |  浏览/下载:66/0  |  提交时间:2021/11/04
Inhibiting mechanism of small molecule toward the p53-MDM2 interaction: A molecular dynamic exploration 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 92, 期号: 4, 页码: 1763-1777
作者:  Chen, Jianzhong;  Wang, Jinan;  Pang, Laixue;  Zhu, Weiliang
收藏  |  浏览/下载:40/0  |  提交时间:2019/01/08
Probing Origin of Binding Difference of inhibitors to MDM2 and MDMX by Polarizable Molecular Dynamics Simulation and QM/MM-GBSA Calculation 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Chen, Jianzhong;  Wang, Jinan;  Zhang, Qinggang;  Chen, Kaixian;  Zhu, Weiliang
收藏  |  浏览/下载:20/0  |  提交时间:2019/01/08
A computational analysis of binding modes and conformation changes of MDM2 induced by p53 and inhibitor bindings 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2013, 卷号: 27, 期号: 11, 页码: 965-974
作者:  Chen, Jianzhong;  Wang, Jinan;  Zhu, Weiliang;  Li, Guohui
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Insight into mechanism of small molecule inhibitors of the MDM2-p53 interaction: Molecular dynamics simulation and free energy analysis 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2011, 卷号: 30, 页码: 46-53
作者:  Chen, Jianzhong;  Wang, Jinan;  Xu, Beisi;  Zhu, Weiliang;  Li, Guohui
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08


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