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科研机构
上海药物研究所 [49]
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期刊论文 [45]
会议论文 [3]
项目 [1]
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2021 [4]
2019 [2]
2017 [3]
2016 [4]
2014 [4]
2013 [1]
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Pharmacolo... [1]
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Medicines for Malaria Venture
项目
资助机构: Medicines for Malaria Venture, 2021-
-
收藏
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浏览/下载:2/0
  |  
提交时间:2021/11/04
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
期刊论文
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:
Shackleford, David M.
;
Chiu, Francis C. K.
;
Katneni, Kasiram
;
Blundell, Scott
;
McLaren, Jenna
收藏
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浏览/下载:59/0
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提交时间:2021/11/04
OZ439 (artefenomel)
malaria
metabolite identification
cytochrome P450 metabolism
cytochrome P450 inhibition
time-dependent inhibition
Full-Length Transcriptome Analysis of Plasmodium falciparum by Single-Molecule Long-Read Sequencing
期刊论文
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2021, 卷号: 11, 页码: 11
作者:
Yang, Mengquan
;
Shang, Xiaomin
;
Zhou, Yiqing
;
Wang, Changhong
;
Wei, Guiying
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
Plasmodium falciparum
small protein
long non-coding RNA
alternative splicing
full-length RNA-seq
In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues
期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 卷号: 65, 期号: 2, 页码: 11
作者:
Uche, Fidelia Ijeoma
;
Guo, Xiaozhen
;
Okokon, Jude
;
Ullah, Imran
;
Horrocks, Paul
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
malaria
Plasmodium falciparum
Plasmodium berghei
bisbenzylisoquinoline alkaloids
cycleanine
metabolism
in vivo activity
antimalarial agents
drug metabolism
Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase
期刊论文
ACS INFECTIOUS DISEASES, 2020, 卷号: 6, 期号: 11, 页码: 2994-3003
作者:
Butler, Joshua H.
;
Baptista, Rodrigo P.
;
Valenciano, Ana L.
;
Zhou, Bin
;
Kissinger, Jessica C.
收藏
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浏览/下载:14/0
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提交时间:2021/05/24
Plasmodium
PfPARE
structure-resistance relationship study
Malaria Box
Pathogen Box
lindenane sesquiterpenoid dimers
Quantitative Analysis of Artemisinin Derivatives: Applications and Techniques
期刊论文
SEPARATION AND PURIFICATION REVIEWS, 2019, 卷号: 48, 期号: 3, 页码: 242-266
作者:
Zhang, Lili
;
Jiang, Yanyan
;
Li, Ning
;
Pu, Yiqiong
;
Zhang, Tong
收藏
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浏览/下载:9/0
  |  
提交时间:2020/07/01
Artemisinin derivatives
quantitative analysis
spectroscopy
chromatography
mass spectrometry
Biological Activities of Artemisinin Derivatives Beyond Malaria
期刊论文
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 3, 页码: 205-222
作者:
Liu, Xiaoyan
;
Cao, Jianguo
;
Huang, Guozheng
;
Zhao, Qingjie
;
Shen, Jingshan
收藏
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浏览/下载:6/0
  |  
提交时间:2020/07/01
Anticancer activity
Antiviral activity
Artemisinin
Artemisinin derivatives
Dimer
Trimer
Structure-activity relationships of the antimalarial agent artemisinin and the research progress on the artemisinin analogues with novel pharmacological actions
期刊论文
Kexue Tongbao/Chinese Science Bulletin, 2017, 卷号: 62, 期号: 18, 页码: 1948-1963
作者:
Zheng, Mingyue
;
Liu, Gang
;
Tang, Wei
;
Zuo, Jianping
;
Zhang, Ao
收藏
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浏览/下载:13/0
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提交时间:2019/01/08
Nanomolar Antimalarial Agents against Chloroquine-Resistant Plasmodium falciparum from Medicinal Plants and Their Structure-Activity Relationships
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 1, 页码: 96-107
作者:
Zhou, Bin
;
Wu, Yan
;
Dalal, Seema
;
Merino, Emilio F.
;
Liu, Qun-Fang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Solvents effects on crystallinity and dissolution of beta-artemether
期刊论文
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2017, 卷号: 43, 期号: 3, 页码: 372-378
作者:
Xu, Jianghui
;
Singh, Vikramjeet
;
Yin, Xianzhen
;
Singh, Parbeen
;
Wu, Li
收藏
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浏览/下载:20/0
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提交时间:2019/01/08
beta-artemether
polymorphic forms
dissolution rate
crystal habits
recrystallization
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