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CORC

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5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing
收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:  Chen, Yun;  Bai, Gang;  Li, Yan;  Ning, Yi;  Cao, Sufen
收藏  |  浏览/下载：32/0  |  提交时间：2021/12/01
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16
Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 906, 页码: 8
作者:  Xiao, Meng-Chao;  Qian, Hui;  Huang, Chen-Kai;  Zheng, Bai-Nan;  Yan, Fang-Zhi
收藏  |  浏览/下载：51/0  |  提交时间：2021/11/04
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming
收藏  |  浏览/下载：38/0  |  提交时间：2021/05/24
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia 期刊论文
CHEMMEDCHEM, 2021, 页码: 12
作者:  Jin, Tingting;  Wang, Peipei;  Long, Xiubing;  Jiang, Kailong;  Song, Pinrao
收藏  |  浏览/下载：133/0  |  提交时间：2021/05/24
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:  Qiu, Xiaqiu;  Li, Yuanqing;  Yu, Bin;  Ren, Jie;  Huang, Huidan
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
CDK9  Antitumor  PROTAC  AML  Degrader  
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:  Zhang, Xiao-tuan;  Hu, Xiao-bei;  Wang, Han-lin;  Kan, Wei-juan;  Xu, Lei
收藏  |  浏览/下载：51/0  |  提交时间：2020/12/24
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:  Wang, Zheng;  Li, Zeng-xia;  Zhao, Wen-cao;  Huang, Hong-bo;  Wang, Jia-qi
收藏  |  浏览/下载：85/0  |  提交时间：2020/12/24
A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe 期刊论文
Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1
作者:  Hu,Liangning;  Li,Bo;  Chen,Gege;  Song,Dongliang;  Xu,Zhijian
收藏  |  浏览/下载：94/0  |  提交时间：2020/07/01

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