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MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice 期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 119, 页码: 12
作者:  Xu, Xiaoding;  Dong, Yunxia;  Ma, Ningning;  Kong, Weiwen;  Yu, Chuwei
收藏  |  浏览/下载:31/0  |  提交时间:2021/08/17
New PCSK9 inhibitor miR-552-3p reduces LDL-C via enhancing LDLR in high fat diet-fed mice 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 167, 页码: 13
作者:  Ma, Ningning;  Fan, Lei;  Dong, Yunxia;  Xu, Xiaoding;  Yu, Chuwei
收藏  |  浏览/下载:49/0  |  提交时间:2021/08/17
Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism 期刊论文
NATURE METABOLISM, 2021, 页码: 31
作者:  Xu, Yanyong;  Li, Yuanyuan;  Jadhav, Kavita;  Pan, Xiaoli;  Zhu, Yingdong
收藏  |  浏览/下载:35/0  |  提交时间:2021/05/24
Lipid-Lowering Activities of Cucurbitacins Isolated from Trichosanthes cucumeroides and Their Synthetic Derivatives 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020, 卷号: 83, 期号: 12, 页码: 3536-3544
作者:  Zhang, Xianjing;  Li, Huihui;  Wang, Wenqiong;  Chen, Tong;  Xuan, Lijiang
收藏  |  浏览/下载:16/0  |  提交时间:2021/05/24
23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 327-335
作者:  Li, Hui-hui;  Li, Jun;  Zhang, Xian-jing;  Li, Jiao-meng;  Xi, Cong
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/01
pcsk9与多种代谢相关疾病发生发展关系的研究进展 期刊论文
中国新药杂志, 2020, 卷号: 29, 期号: 5, 页码: 507
作者:  范磊;  陈静;  任进
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/01
2324dihydrocucurbitacinbpromoteslipidclearancebydualtranscriptionalregulationofldlrandpcsk9 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 327
作者:  Li Huihui;  Li Jun;  Zhang Xianjing;  Li Jiaomeng;  Xi Cong
收藏  |  浏览/下载:44/0  |  提交时间:2020/07/01
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:  Wu, Chenglin;  Xi, Cong;  Tong, Junhua;  Zhao, Jing;  Jiang, Hualiang
收藏  |  浏览/下载:50/0  |  提交时间:2020/07/01
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia 期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:  Wu Chenglin;  Xi Cong;  Tong Junhua;  Zhao Jing;  Jiang Hualiang
收藏  |  浏览/下载:54/0  |  提交时间:2020/07/01
Indole alkaloid from Nauclea latifolia promotes LDL uptake in HepG2 cells by inhibiting PCSK9 期刊论文
Phytomedicine, 2018
作者:  Aggrey, Mike Okweesi;  Li, Hui-Hui;  Wang, Wen-Qiong;  Wang, Yiping;  Xuan, Li-Jiang
收藏  |  浏览/下载:35/0  |  提交时间:2019/03/13


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