CORC

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CORC

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Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载：41/0  |  提交时间：2022/01/04
Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function 期刊论文
CELL RESEARCH, 2021, 页码: 18
作者:  Xu, Xiang;  Ding, Guangjin;  Liu, Caizhi;  Ding, Yuhan;  Chen, Xiaoxin
收藏  |  浏览/下载：64/0  |  提交时间：2021/11/04
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 15
作者:  Jin, Nan;  Bi, Aiwei;  Lan, Xiaojing;  Xu, Jun;  Wang, Xiaomin
收藏  |  浏览/下载：61/0  |  提交时间：2020/07/01
Development of the First Generation of Disulfide-Based Subtype Selective and Potent Covalent Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 6, 页码: 2227-2244
作者:  Liu, Yifu;  Xie, Zuoquan;  Zhao, Dan;  Zhu, Jin;  Mao, Fei
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08
丙酮酸脱氢酶激酶共价抑制剂JX06抗肿瘤活性和机制研究（英文） 会议论文
作者:  孙文怡;  谢作权;  刘逸夫;  赵丹;  武志翔
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08
JX06 selectively inhibits pyruvate dehydrogenase kinase 1 by covalently targeting a cysteine residue 会议论文
作者:  Sun WY(孙文怡);  Xie ZQ(谢作权);  Liu YF(刘逸夫);  Zhao D(赵丹);  Wu ZX(武志翔)
收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08
BBT improves glucose homeostasis by ameliorating beta-cell dysfunction in type 2 diabetic mice 期刊论文
JOURNAL OF ENDOCRINOLOGY, 2015, 卷号: 224, 期号: 3, 页码: 327-341
作者:  Yao, Xin-gang;  Xu, Xin;  Wang, Gai-hong;  Lei, Min;  Quan, Ling-ling
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
A stress response pathway in mice upregulates somatostatin level and transcription in pancreatic delta cells through Gs and beta-arrestin 1 期刊论文
DIABETOLOGIA, 2014, 卷号: 57, 期号: 9, 页码: 1899-1910
作者:  Wang, Hong-Mei;  Dong, Jun-Hong;  Li, Qing;  Hu, Qiaoxia;  Ning, Shang-Lei
收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08
DW09849, a Selective Phosphatidylinositol 3-Kinase (PI3K) Inhibitor, Prevents PI3K Signaling and Preferentially Inhibits Proliferation of Cells Containing the Oncogenic Mutation p110 alpha (H1047R) 期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2014, 卷号: 348, 期号: 3, 页码: 432-441
作者:  Liu, Jia-li;  Gao, Guo-rui;  Zhang, Xi;  Cao, Su-fen;  Guo, Chen-liang
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08
Clinical pharmacokinetics of small molecule tyrosine kinase inhibitors 期刊论文
Yao xue xue bao = Acta pharmaceutica Sinica, 2013, 卷号: 48, 期号: 7, 页码: 1080-90
作者:  Ding, Jue-Fang;  Zhong, Da-Fang
收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08

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