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科研机构
上海药物研究所 [72]
内容类型
期刊论文 [64]
会议论文 [4]
学位论文 [4]
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2021 [2]
2020 [6]
2019 [1]
2018 [4]
2017 [3]
2016 [11]
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Immunology [1]
Pharmacolo... [1]
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Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583
作者:
Hu, Ke
;
Li, Bo
;
Ma, Ruye
;
Yi, Hongfei
;
Xu, Zhijian
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/06/11
caspase
cell proliferation
cell cycle arrest
diffuse large B-cell lymphoma
PI3K-AKT-mTOR/JNK pathway
A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation
期刊论文
LIFE SCIENCES, 2021, 卷号: 269, 页码: 8
作者:
Yang, Liu
;
Lei, Xian-Tao
;
Huang, Qi
;
Wang, Ting
;
Sun, Hong-Bin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
GPR120 agonist
Insulin secretion
Anti-inflammation
Insulin resistance
Type 2 diabetes mellitus
Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 13
作者:
Xue, Yaru
;
Deng, Qiangqiang
;
Zhang, Qingli
;
Ma, Zhenghua
;
Chen, Binfan
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/24
The Active Constituent From Gynostemma Pentaphyllum Prevents Liver Fibrosis Through Regulation of the TGF-beta 1/NDRG2/MAPK Axis
期刊论文
FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: 11
作者:
Huang, Hui
;
Wang, Kuifeng
;
Liu, Qian
;
Ji, Feihong
;
Zhou, Hu
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/12/24
HSC
TGF-β
1
liver fibrosis
quantitative proteomics
NDRG2
Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Yu, Yan-yan
;
Cui, Shi-chao
;
Zheng, Tian-nan
;
Ma, Hai-jian
;
Xie, Zhi-fu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
insulin resistance
sarsasapogenin
adipose tissue inflammation
macrophage-adipocyte crosstalk
IKK/NF-kappa B
JNK
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:
Xi, Mengyu
;
He, Wan
;
Li, Bo
;
Zhou, Jinfeng
;
Xu, Zhijian
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/12/24
DCZ0801
DLBCL
apoptosis
cell cycle
MAPK
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:
Xi, Mengyu
;
He, Wan
;
Li, Bo
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
DCZ0801
DLBCL
apoptosis
cell cycle
MAPK
Alleviation of Synovial Inflammation of Juanbi-Tang on Collagen-Induced Arthritis and TNF-Tg Mice Model
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 17
作者:
Wang, Tengteng
;
Jia, Qingyun
;
Chen, Tao
;
Yin, Hao
;
Tian, Xiaoting
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
Juanbi-Tang
rheumatoid arthritis
collagen-induced arthritis
synoviocyte
tumor necrosis factor
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer
期刊论文
CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+
作者:
Huang, Ke
;
Liang, Qian
;
Zhou, Ye
;
Jiang, Lu-lu
;
Gu, Wei-ming
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2020/07/01
Antiglioma via regulating oxidative stress and remodeling tumor-associated macrophage using lactoferrin-mediated biomimetic codelivery of simvastatin/fenretinide
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2018, 卷号: 287, 页码: 12-23
作者:
Mo, Xiaopeng
;
Zheng, Zening
;
He, Yang
;
Zhone, Huihai
;
Kane, Xuejia
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
Lactoferrin nanoparticle
Reactive oxygen species
Tumor-associated macrophages
Brain-targeted delivery
Biomimetic delivery
Cell penetrating peptide
Fenretinide
Simvastatin
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