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CORC

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Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:  Xie, Hong-Xu;  Zhang, Juan;  Li, Yue;  Zhang, Jin-He;  Liu, Shan-Kui
收藏  |  浏览/下载：69/0  |  提交时间：2021/11/04
Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855
作者:  Zhou, Yu;  Fu, Yan;  Yin, Wanchao;  Li, Jian;  Wang, Wei
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian
收藏  |  浏览/下载：30/0  |  提交时间：2021/05/24
Diphyllin Improves High-Fat Diet-Induced Obesity in Mice Through Brown and Beige Adipocytes 期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2020, 卷号: 11, 页码: 13
作者:  Duan, Ya-Nan;  Ge, Xiang;  Jiang, Hao-Wen;  Zhang, Hong-Jie;  Zhao, Yu
收藏  |  浏览/下载：42/0  |  提交时间：2021/05/24
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway 期刊论文
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:  Liu, Siwen;  Huang, Suling;  Wu, Xingde;  Feng, Ying;  Shen, Yu
收藏  |  浏览/下载：57/0  |  提交时间：2020/12/24
DGAT1 inhibitors protect pancreatic beta-cells from palmitic acid-induced apoptosis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:  Huang, Jun-shang;  Guo, Bin-bin;  Wang, Gai-hong;  Zeng, Li-min;  Hu, You-hong
收藏  |  浏览/下载：56/0  |  提交时间：2020/12/24
Supramolecular Prodrug Nanovectors for Active Tumor Targeting and Combination Immunotherapy of Colorectal Cancer 期刊论文
ADVANCED SCIENCE, 2020, 页码: 14
作者:  Hu, Xianli;  Hou, Bo;  Xu, Zhiai;  Saeed, Madiha;  Sun, Fang
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01
Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 398-416
作者:  Wang, Yibing;  Lou, Yang;  Wang, Jiang;  Li, Dan;  Chen, Hui
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01
Design, synthesis and antitumor study of a series of N-Cyclic sulfamoylaminoethyl substituted 1,2,5-oxadiazol-3-amines as new indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 179, 页码: 38-55
作者:  Chen, Shulun;  Guo, Wei;  Liu, Xiaohua;  Sun, Pu;  Wang, Yi
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
NLG919/cyclodextrin complexation and anti-cancer therapeutic benefit as a potential immunotherapy in combination with paclitaxel 期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 138, 页码: 8
作者:  Xu, Jian;  Ren, Xiaohong;  Guo, Tao;  Sun, Xian;  Chen, Xiaojin
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01

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