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CORC

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The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 13
作者:  Gao, Feng;  Chen, Xiaoxu;  Lu, Junyan;  Hu, Shulei;  Xu, Hui
收藏  |  浏览/下载：44/0  |  提交时间：2021/05/24
Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20
作者:  Chen, Jingjing;  Li, Yalei;  Zhang, Jie;  Zhang, Minmin;  Wei, Aihuan
收藏  |  浏览/下载：27/0  |  提交时间：2021/05/24
PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma 期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403
作者:  Wang, Jianfeng;  Wang, Chen;  Xu, Pan;  Li, Xiao;  Lu, Yongning
收藏  |  浏览/下载：130/0  |  提交时间：2021/05/24
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Dai, Meng-di;  Wang, Yue-liang;  Fan, Jun;  Dai, Yang;  Ji, Yin-chun
收藏  |  浏览/下载：33/0  |  提交时间：2021/05/24
Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 16, 页码: 6
作者:  Su, Zhicheng;  Yang, Tingyuan;  Wang, Jie;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载：28/0  |  提交时间：2020/12/24
EGFR  NSCLC  C797S  
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan
收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24
Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1) 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 195, 页码: 13
作者:  Zhang, Shiyan;  Huang, Chaoying;  Lyu, Xilin;  Wang, Peipei;  Zang, Yi
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01
BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis 期刊论文
THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12
作者:  Li, Guang;  Zheng, Yan-Hua;  Xu, Li;  Feng, Juan;  Tang, Hai-Long
收藏  |  浏览/下载：50/0  |  提交时间：2020/12/24
A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 11
作者:  Lu, Kang;  Li, Bo;  Zhang, Hui;  Xu, Zhijian;  Song, Dongliang
收藏  |  浏览/下载：58/0  |  提交时间：2020/07/01

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