CORC

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CORC

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Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439 期刊论文
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:  Shackleford, David M.;  Chiu, Francis C. K.;  Katneni, Kasiram;  Blundell, Scott;  McLaren, Jenna
收藏  |  浏览/下载：59/0  |  提交时间：2021/11/04
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:  Wu, Ya-li;  Xue, Ya-ru;  Guo, Zi-tao;  Chen, Zhen-dong;  Ge, Xin-yu
收藏  |  浏览/下载：22/0  |  提交时间：2021/08/17
Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China 期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 1, 页码: 5-23
作者:  Yu, Xuan;  Chu, Zixuan;  Li, Jian;  He, Rongrong;  Wang, Yaya
收藏  |  浏览/下载：69/0  |  提交时间：2021/05/24
Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  Liu, Xiao-yun;  Guo, Zi-tao;  Chen, Zhen-dong;  Zhang, Yi-fan;  Zhou, Jia-lan
收藏  |  浏览/下载：80/0  |  提交时间：2020/07/01
The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor 期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 45, 期号: 1, 页码: 15-26
作者:  Zhang, Leduo;  Mao, Yu;  Gao, Zhiwei;  Chen, Xiaoyan;  Li, Xin
收藏  |  浏览/下载：49/0  |  提交时间：2020/07/01
Differences in the In Vivo and In Vitro Metabolism of Imrecoxib in Humans: Formation of the Rate-Limiting Aldehyde Intermediate 期刊论文
DRUG METABOLISM AND DISPOSITION, 2018, 卷号: 46, 期号: 9, 页码: 1320-1328
作者:  Hou, Xiangyu;  Zhou, Jialan;  Yu, Songda;  Zhou, Lei;  Zhang, Yifan
收藏  |  浏览/下载：71/0  |  提交时间：2019/01/08
CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1386-1392
作者:  Xu, Ye;  Zhang, Yi-fan;  Chen, Xiao-yan;  Zhong, Da-fang
收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08
Effect of Fluconazole on the Pharmacokinetic Properties of Imrecoxib, a Novel NSAID: A Single-center, Open-label, Self-controlled Study in Healthy Chinese Male Volunteers 期刊论文
CLINICAL THERAPEUTICS, 2018, 卷号: 40, 期号: 8, 页码: 1347-1356
作者:  Zuo, Cheng-zi;  Gong, Yi;  Hou, Xiang-yu;  Zhang, Yi-fan;  Peng, Wen-xing
收藏  |  浏览/下载：75/0  |  提交时间：2019/01/08
cyp3a4inducerandinhibitorstronglyaffectthepharmacokineticsoftriptolideanditsderivativeinrats 期刊论文
actapharmacologicasinica, 2018, 卷号: 039, 期号: 008, 页码: 1386
作者:  Xu Ye;  Zhang Yifan;  Chen Xiaoyan;  Zhong Dafang
收藏  |  浏览/下载：3/0  |  提交时间：2020/07/01
Metabolism of diosbulbin B in vitro and in vivo in rats: formation of reactive metabolites and human enzymes involved 期刊论文
Drug metabolism and disposition: the biological fate of chemicals, 2014, 卷号: 42, 期号: 10, 页码: 1737-50
作者:  Yang, Baohua;  Liu, Wei;  Chen, Kaixian;  Wang, Zhengtao;  Wang, Changhong
收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08

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