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科研机构
上海药物研究所 [20]
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期刊论文 [20]
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2021 [1]
2020 [3]
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A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage
期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 120, 页码: 12
作者:
Huang, Suling
;
Wu, Yanwei
;
Zhao, Zhuohui
;
Wu, Bing
;
Sun, Kai
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2021/08/17
Macrophage
NLRP3 inflammasome
Hepatic lipid accumulation
NASH
FXR
Neonatal exposure to ketamine disrupts developmental synapse unsilencing and predisposes adult mice for stressor-evoked anxiety
期刊论文
NEUROPHARMACOLOGY, 2020, 卷号: 180, 页码: 12
作者:
Zhang, Xiaoyun
;
Kong, Yue
;
He, Guiqin
;
Zhou, Zikai
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/05/24
Stress
Anxiety
Silent synapse
Long-term potentiation
Anesthesia
The impact of structural modification of sulfated polysaccharides on bone morphogenic protein 2 and inhibition of endothelial cell angiogenesis
期刊论文
CARBOHYDRATE RESEARCH, 2020, 卷号: 496, 页码: 10
作者:
Wang, Ying
;
Xiao, Fei
;
Jin, Can
;
Wang, Wucheng
;
Chen, Xia
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/21
Sulfated polysaccharides
Bone morphogenic protein 2
Structure and activity relationship
Angiogenesis
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way
期刊论文
FASEB JOURNAL, 2020, 页码: 16
作者:
Wu, Yanwei
;
Wu, Bing
;
Zhang, Zongwang
;
Lu, Huimin
;
Fan, Chen
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
IBD
M1
M2
ulcerative colitis
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595
作者:
Zhang, Kai-li
;
Shen, Qian-qian
;
Fang, Yan-fen
;
Sun, Yi-ming
;
Ding, Jian
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
PRC2
EZH2-EED
AZD9291
miR-34a
non-canonical base pairing
Natural Brain Penetration Enhancer-Modified Albumin Nanoparticles for Glioma Targeting Delivery
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2018, 卷号: 10, 期号: 36, 页码: 30201-30213
作者:
Liang, Jianming
;
Gao, Caifang
;
Zhu, Ying
;
Ling, Chengli
;
Wang, Qi
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/01/08
brain penetration enhancer
menthol
glioma
brain permeability
BBB-disrupting
pineal gland
The Mechanism by Which Luteolin Disrupts the Cytoplasmic Membrane of Methicillin-Resistant Staphylococcus aureus
期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2018, 卷号: 122, 期号: 4, 页码: 1427-1438
作者:
Zhang, Tao
;
Qiu, Yunguang
;
Luo, Qichao
;
Zhao, Lifen
;
Yan, Xin
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents
期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 24, 页码: 20578-20591
作者:
Lin, Chenchu
;
Zeng, Hanlin
;
Lu, Junyan
;
Xie, Zuoquan
;
Sun, Wenyi
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
acetylation
camptothecin
SIRT1
superoxide dismutase
oxidative stress
Disruption of the unfolded protein response (UPR) by lead compound selectively suppresses cancer cell growth
期刊论文
CANCER LETTERS, 2015, 卷号: 360, 期号: 2, 页码: 257-268
作者:
Huang, Hejing
;
Liu, Huanan
;
Liu, Changmei
;
Fan, Lixia
;
Zhang, Xinwen
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Selective cancer therapy
Unfolded protein response
2DG
UPR disrupter
MCL-1 Degradation Mediated by JNK Activation via MEKK1/TAK1-MKK4 Contributes to Anticancer Activity of New Tubulin Inhibitor MT189
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2014, 卷号: 13, 期号: 6, 页码: 1480-1491
作者:
Wang, Wei
;
Wang, Ying-Qing
;
Meng, Tao
;
Yi, Jun-Mei
;
Huan, Xia-Juan
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
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