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Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/01
discoveryandbiologicalevaluationofn372methoxy44methylpiperazin1ylphenylamino4methyl2oxo2hpyrimido45d13oxazin14hylphenylacrylamideaspotentbrutonstyrosinekinaseinhibitors 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 415
作者:  Lai Mengzhen;  Song Peiran;  Dou Dou;  Diao Yanyan;  Tong Linjiang
收藏  |  浏览/下载:31/0  |  提交时间:2020/07/01
Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-A beta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 21
作者:  Jiang, Cheng-Shi;  Ge, Yong-Xi;  Cheng, Zhi-Qiang;  Wang, Yin-Yin;  Tao, Hong-Rui
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/01
Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689
作者:  Wang, Qi;  Dai, Yang;  Ji, Yinchun;  Shi, Huanyu;  Guo, Zuhao
收藏  |  浏览/下载:89/0  |  提交时间:2019/01/08
Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors 期刊论文
Bioorganic chemistry, 2018, 卷号: 83, 页码: 277-288
作者:  Cheng, Zhi-Qiang;  Zhu, Kong-Kai;  Zhang, Juan;  Song, Jia-Li;  Muehlmann, Luis Alexandre
收藏  |  浏览/下载:51/0  |  提交时间:2019/01/08
Extra Sugar on Vancomycin: New Analogues for Combating Multidrug-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 1, 页码: 286-304
作者:  Guan, Dongliang;  Chen, Feifei;  Xiong, Lun;  Tang, Feng;  Faridoon
收藏  |  浏览/下载:31/0  |  提交时间:2019/01/08
Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 3, 页码: 778-781
作者:  Zhang, Li;  Jiang, Cheng-Shi;  Gao, Li-Xin;  Gong, Jing-Xu;  Wang, Zhong-Hua
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Design and synthesis of novel 1,2-dithiolan-4-yl benzoate derivatives as PTP1B inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 10, 页码: 2211-2216
作者:  Chen, Jing;  Gao, Li-Xin;  Gong, Jing-Xu;  Jiang, Cheng-Shi;  Yao, Li-Gong
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Determination of pK(a) values of a triptolide derivative and its impurities by pressure-assisted capillary electrophoresis 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014, 卷号: 88, 页码: 22-26
作者:  Wang, Jian-Ling;  Xu, Xue-Jiao;  Chen, Dong-Ying
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 69, 页码: 399-412
作者:  Chen, Yue-Ting;  Tang, Chun-Lan;  Ma, Wei-Ping;  Gao, Li-Xin;  Wei, Yi
收藏  |  浏览/下载:10/0  |  提交时间:2019/01/08


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