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CORC

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Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing
收藏  |  浏览/下载：32/0  |  提交时间：2021/12/16
Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition 期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 6, 页码: 1929-1936
作者:  Gao, Jing;  Zhang, Hanwu;  Zhou, Fengqi;  Hou, Bo;  Chen, Meiwan
收藏  |  浏览/下载：17/0  |  提交时间：2021/08/17
Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583
作者:  Hu, Ke;  Li, Bo;  Ma, Ruye;  Yi, Hongfei;  Xu, Zhijian
收藏  |  浏览/下载：71/0  |  提交时间：2021/06/11
Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 12
作者:  Lin, Tingting;  Li, Jiacheng;  Liu, Liping;  Li, Yuanqing;  Jiang, Hualiang
收藏  |  浏览/下载：73/0  |  提交时间：2021/05/24
Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury 期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 7, 页码: 925-941
作者:  Liu, Yanjun;  Li, Jiacheng;  Liao, Liping;  Huang, Heming;  Fan, Shijie
收藏  |  浏览/下载：21/0  |  提交时间：2021/08/17
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:  Qiu, Xiaqiu;  Li, Yuanqing;  Yu, Bin;  Ren, Jie;  Huang, Huidan
收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24
CDK9  Antitumor  PROTAC  AML  Degrader  
Global and Site-Specific Effect of Phosphorylation on Protein Turnover 期刊论文
DEVELOPMENTAL CELL, 2021, 卷号: 56, 期号: 1, 页码: 111-+
作者:  Wu, Chongde;  Ba, Qian;  Lu, Dayun;  Li, Wenxue;  Salovska, Barbora
收藏  |  浏览/下载：25/0  |  提交时间：2021/05/24
EZH2 inhibitors abrogate upregulation of trimethylation of H3K27 by CDK9 inhibitors and potentiate its activity against diffuse large B-cell lymphoma 期刊论文
HAEMATOLOGICA, 2020, 卷号: 105, 期号: 4, 页码: 1021-1031
作者:  Xie, Shao;  Wei, Fan;  Sun, Yi-ming;  Gao, Ying-lei;  Pan, Lu-lu
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:  Xi, Mengyu;  He, Wan;  Li, Bo;  Zhou, Jinfeng;  Xu, Zhijian
收藏  |  浏览/下载：45/0  |  提交时间：2020/12/24
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:  Xi, Mengyu;  He, Wan;  Li, Bo;  Zhou, Jinfeng
收藏  |  浏览/下载：23/0  |  提交时间：2020/12/24

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