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科研机构
上海药物研究所 [68]
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期刊论文 [68]
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2021 [5]
2020 [6]
2019 [9]
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Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma
期刊论文
CHEMICAL ENGINEERING JOURNAL, 2021, 卷号: 417, 页码: 11
作者:
Geng, Huan
;
Zhou, Mengxue
;
Li, Bin
;
Liu, Liang
;
Yang, Xu
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
Metal-drug nanoparticles
Orthotopic osteosarcoma
Osteolytic microenvironment
Zoledronate
Radiotherapy
Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 7, 页码: 1885-1902
作者:
Wu, Xu
;
Yin, Chun
;
Ma, Jiang
;
Chai, Stella
;
Zhang, Chunyuan
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/11/04
Multidrug resistance
ABCB1
Polyoxypregnane
Combination chemotherapy
Marsdenia tenacissima
Engineering Oxaliplatin Prodrug Nanoparticles for Second Near-Infrared Fluorescence Imaging-Guided Immunotherapy of Colorectal Cancer
期刊论文
SMALL, 2021, 卷号: 17, 期号: 13, 页码: 11
作者:
Zhu, Qiurong
;
Sun, Fang
;
Li, Tianliang
;
Zhou, Mengxue
;
Ye, Jiayi
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2021/05/24
colorectal cancer
combinatory immunotherapy
immunogenic cell death
prodrug nanoparticles
second near‐
infrared fluorescence imaging
Overcoming immune resistance by sequential prodrug nanovesicles for promoting chemoimmunotherapy of cancer
期刊论文
NANO TODAY, 2021, 卷号: 36, 页码: 12
作者:
Zhou, Fengqi
;
Gao, Jing
;
Xu, Zhiai
;
Li, Tianliang
;
Gao, Ang
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/06/11
Tumor microenvironment
Prodrug nanovesicles
Cancer immunotherapy
Immunogenic cell death
Adaptive immune resistance
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models
期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 卷号: 11, 期号: 4, 页码: 1632-1645
作者:
Wang, Lei
;
Zhu, Xi
;
Li, Lili
;
Li, Lin
;
Fu, Li
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2021/06/11
PARP
DNA damage
hematologic toxicity
beta-glucuronidase
tumor selectivity
Ternary Regulation of Tumor Microenvironment by Heparanase-Sensitive Micelle-Loaded Monocytes Improves Chemo-Immunotherapy of Metastatic Breast Cancer
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 12
作者:
Lang, Tianqun
;
Zheng, Zhong
;
Huang, Xin
;
Liu, Yiran
;
Zhai, Yihui
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/05/24
breast cancer
chemo-immunotherapy
heparinase
monocytes
tumor environments
Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
He, Zhi-di
;
Zhang, Meng
;
Wang, Yong-hui
;
He, Yang
;
Wang, Hai-rui
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
tumor-targeted delivery
immunogenic cell death
PD-1
PD-L1 blockade
tumor immune microenvironment
irinotecan
JQ1
immune checkpoint
Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2020, 卷号: 46, 期号: 6, 页码: 2137-2149
作者:
Pan, Lijia
;
Nie, Litong
;
Yao, Sheng
;
Bi, Aiwei
;
Ye, Yang
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
neuroblastoma
bufalin
chemical proteomics
ETC
mitochondria
Supramolecular Drug-Drug Complex Vesicles Enable Sequential Drug Release for Enhanced Combination Therapy
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2020, 卷号: 12, 期号: 25, 页码: 27940-27950
作者:
Liu, Chengfei
;
Li, Chunpu
;
Pang, Cui
;
Li, Muqiong
;
Li, Huixin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
drug-drug self-delivery system
supramolecular vesicles
host-guest interaction
self-assembly
pillar[5]arene
combination therapy
BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis
期刊论文
THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12
作者:
Li, Guang
;
Zheng, Yan-Hua
;
Xu, Li
;
Feng, Juan
;
Tang, Hai-Long
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/12/24
apoptosis
BRD4 inhibitor
G1 phase cell cycle checkpoint
multiple myeloma
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