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Structural Insights into Chitinolytic Enzymes and Inhibition Mechanisms of Selective Inhibitors 期刊论文
CURRENT PHARMACEUTICAL DESIGN, 2014, 卷号: 20, 期号: 5, 页码: 754-770
作者:  Liu, Tian;  Chen, Lei;  Ma, Qiang;  Shen, Xu;  Yang, Qing
收藏  |  浏览/下载:10/0  |  提交时间:2019/01/08
Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 19, 页码: 5963-5972
作者:  Serrao, Erik;  Xu, Zhong-Liang;  Debnath, Bikash;  Christ, Frauke;  Debyser, Zeger
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
Caffeic acid phenethyl ester (CAPE), an active component of propolis, inhibits Helicobacter pylori peptide deformylase activity 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013, 卷号: 435, 期号: 2, 页码: 289-294
作者:  Cui, Kunqiang;  Lu, Weiqiang;  Zhu, Lili;  Shen, Xu;  Huang, Jin
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
In Vitro Studies on the Oxidative Metabolism of 20(S)-Ginsenoside Rh2 in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes, and Human Liver S9 期刊论文
DRUG METABOLISM AND DISPOSITION, 2012, 卷号: 40, 期号: 10, 页码: 2041-2053
作者:  Li, Liang;  Chen, Xiaoyan;  Zhou, Jialan;  Zhong, Dafang
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Active-pocket size differentiating insectile from bacterial chitinolytic beta-N-acetyl-D-hexosaminidases 期刊论文
BIOCHEMICAL JOURNAL, 2011, 卷号: 438, 页码: 467-474
作者:  Liu, Tian;  Zhang, Haitao;  Liu, Fengyi;  Chen, Lei;  Shen, Xu
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
Molecular Basis of NDM-1, a New Antibiotic Resistance Determinant 期刊论文
PLOS ONE, 2011, 卷号: 6, 期号: 8
作者:  Liang, Zhongjie;  Li, Lianchun;  Wang, Yuanyuan;  Chen, Limin;  Kong, Xiangqian
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations 期刊论文
PROTEIN SCIENCE, 2011, 卷号: 20, 期号: 7, 页码: 1114-1118
作者:  Sanson, Benoit;  Colletier, Jacques-Philippe;  Xu, Yechun;  Lang, P. Therese;  Jiang, Hualiang
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08
Structural Determinants of an Insect beta-N-Acetyl-D-hexosaminidase Specialized as a Chitinolytic Enzyme 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 卷号: 286, 期号: 6, 页码: 4049-4058
作者:  Liu, Tian;  Zhang, Haitao;  Liu, Fengyi;  Wu, Qingyue;  Shen, Xu
收藏  |  浏览/下载:10/0  |  提交时间:2019/01/08
Investigation of the Catalytic Mechanism of Sir2 Enzyme with QM/MM Approach: SN1 vs SN2? 期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2010, 卷号: 114, 期号: 36, 页码: 11927-11933
作者:  Liang, Zhongjie;  Shi, Ting;  Ouyang, Sisheng;  Li, Honglin;  Yu, Kunqian
收藏  |  浏览/下载:24/0  |  提交时间:2019/01/08
Dual role of Zn2+ in maintaining structural integrity and suppressing deacetylase activity of SIRT1 期刊论文
JOURNAL OF INORGANIC BIOCHEMISTRY, 2010, 卷号: 104, 期号: 2, 页码: 180-185
作者:  Chen, Lei;  Feng, Yu;  Zhou, Yinqiu;  Zhu, Weiliang;  Shen, Xu
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08


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