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科研机构
上海药物研究所 [19]
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期刊论文 [19]
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2021 [2]
2020 [1]
2019 [3]
2018 [7]
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专题:上海药物研究所
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Graphene nanoribbon-based supramolecular ensembles with dual-receptor targeting function for targeted photothermal tumor therapy
期刊论文
CHEMICAL SCIENCE, 2021, 页码: 9
作者:
Dou, Wei-Tao
;
Xu, Fugui
;
Xu, Chen-Xi
;
Gao, Jie
;
Ru, Hong-Bo
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/08/17
CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis
期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 20, 页码: 9821-9832
作者:
Li, Xiaoxun
;
Liang, Yajun
;
Lian, Cheng
;
Peng, Fangli
;
Xiao, Yansen
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/04
Breast cancer
Bone metastasis
Osteoclastogenesis
CST6
Peptide drug
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10
作者:
Hou, Zeng
;
Min, Wenjian
;
Zhang, Rukang
;
Niu, Ao
;
Li, Yuanqing
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  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
Histone methylation
SET7
Small-molecule inhibitor
Virtual screening
Molecular probe
Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 21
作者:
Chen, Deheng
;
Lu, Tian
;
Yan, Ziqin
;
Lu, Wenchao
;
Lyu, Xilin
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  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Bromodomain
BET protein
BD2
Selective
Crystal structure
Design, synthesis, and biological evaluation of a new class of histone acetyltransferase p300 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 171-190
作者:
Liu, Ruiqi
;
Zhang, Zhuqing
;
Yang, Hong
;
Zhou, Kaixin
;
Geng, Meiyu
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
p300 inhibitors
Epigenetics
Structure-activity relationship
Sensitive tumor cell proliferation
C646
Self-Assembled 2D Glycoclusters for the Targeted Delivery of Theranostic Agents to Triple-Negative Breast Cancer Cells
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 期号: 25, 页码: 22181-22187
作者:
Hu, Xi-Le
;
Ca, Quanyu
;
Gao, Jie
;
Field, Robert A.
;
Chen, Guo-Rong
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  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
self-assembly
2D material
glycocluster
theranostics
breast cancer
Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors
期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 281-294
作者:
Xing, Jing
;
Zhang, Rukang
;
Jiang, Xiangrui
;
Hu, Tianwen
;
Wang, Xinjun
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  |  
浏览/下载:89/0
  |  
提交时间:2019/01/08
Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice
期刊论文
Phytotherapy research : PTR, 2018
作者:
Xu, Ying
;
Li, Xin
;
Chen, Ting
;
Qu, Ya-Kun
;
Zheng, Hong-Xia
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/01/08
Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503
作者:
Dong, Jiajia
;
Olaleye, Olajide E.
;
Jiang, Rongrong
;
Li, Jing
;
Lu, Chuang
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2019/01/08
Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 15, 页码: 6685-6704
作者:
Qin, Chong
;
Hu, Yang
;
Zhou, Bing
;
Fernandez-Salas, Ester
;
Yang, Chao-Yie
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
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