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科研机构
上海药物研究所 [14]
内容类型
期刊论文 [14]
发表日期
2021 [1]
2020 [2]
2019 [1]
2017 [3]
2016 [2]
2013 [1]
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Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy
期刊论文
Chinese Medicine, 2021, 卷号: 16, 期号: 1
作者:
Wu,Gaosong
;
Zhao,Jing
;
Zhao,Jing
;
Song,Nixue
;
Zheng,Ningning
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/01
Coronary heart disease
Syndrome differentiation
Traditional Chinese Medicine
Proteomics
Metabolomics
Network pharmacology
Integrin beta 3 Deficiency Results in Hypertriglyceridemia via Disrupting LPL (Lipoprotein Lipase) Secretion
期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2020, 卷号: 40, 期号: 5, 页码: 1296-1310
作者:
Xiao, Bing
;
Mao, Jianhua
;
Sun, Boyang
;
Zhang, Wei
;
Wang, Yun
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
integrins
lipoprotein lipase
lipoproteins
protein kinase D
thrombasthenia
Intestinal microbes derived butyrate is related to the immunomodulatory activities of Dendrobium officinale polysaccharide
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 149, 页码: 717-723
作者:
Li, Meixia
;
Yue, Han
;
Wang, Yeqing
;
Guo, Ciliang
;
Du, Zhenyun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Dendrobium officinale
Polysaccharide
Gut microbiota
Metagenomics sequencing
SCFAs
TGR5 agonist ameliorates insulin resistance in skeletal muscles and improves glucose homeostasis in diabetic mice
期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2019, 卷号: 99, 页码: 45-56
作者:
Huang, Suling
;
Ma, Shanyao
;
Ning, Mengmeng
;
Yang, Wenji
;
Ye, Yangliang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
TGR5
Glucose homeostasis
Insulin resistance
Skeletal muscle
Type 2 diabetes
A novel glucagon-like peptide-1/glucagon receptor dual agonist exhibits weight-lowering and diabetes-protective effects
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 1158-1169
作者:
Zhou, Jie
;
Cai, Xingguang
;
Huang, Xun
;
Dai, Yuxuan
;
Sun, Lidan
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Glucagon
GLP-1/GCGR agonist
Weight-lowering
Diabetes-protective
Amyloid beta: structure, biology and structure-based therapeutic development
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 9, 页码: 1205-1235
作者:
Chen, Guo-fang
;
Xu, Ting-hai
;
Yan, Yan
;
Zhou, Yu-ren
;
Jiang, Yi
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
amyloid beta peptide
amyloid precursor protein
Alzheimer's disease
neurodegenerative diseases
drug discovery
amyloidbetastructurebiologyandstructurebasedtherapeuticdevelopment
期刊论文
actapharmacologicasinica, 2017, 卷号: 38, 期号: 9, 页码: 1205
作者:
Chen Guofang
;
Xu Tinghai
;
Yan Yan
;
Zhou Yuren
;
Jiang Yi
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/07/01
BLOOD-BRAIN-BARRIER
INSULIN-DEGRADING ENZYME
SOLID-STATE NMR
NICOTINIC ACETYLCHOLINE-RECEPTORS
METABOTROPIC GLUTAMATE RECEPTORS
ATOMIC-FORCE MICROSCOPY
GAMMA-SECRETASE COMPLEX
SMOOTH-MUSCLE-CELLS
AMELIORATES MEMORY IMPAIRMENT
ENDOTHELIN-CONVERTING ENZYME
amyloid beta peptide
amyloid precursor protein
Alzheimer's disease
neurodegenerative diseases
drug discovery
Design, synthesis and biological evaluation of novel non-covalent piperidine-containing peptidyl proteasome inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 23, 页码: 6206-6214
作者:
Zhang, Jiankang
;
Gao, Lixin
;
Xi, Jianjun
;
Sheng, Li
;
Zhao, Yanmei
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
Proteasome inhibitors
Piperidine
Non-covalent
Anti-cancer
SARs
miR-182 Regulates Metabolic Homeostasis by Modulating Glucose Utilization in Muscle
期刊论文
CELL REPORTS, 2016, 卷号: 16, 期号: 3, 页码: 757-768
作者:
Zhang, Duo
;
Li, Yan
;
Yao, Xuan
;
Wang, Hui
;
Zhao, Lei
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Metabolism studies of unformulated internally [3H]-labeled short interfering RNAs in mice
期刊论文
Drug metabolism and disposition: the biological fate of chemicals, 2013, 卷号: 41, 期号: 6, 页码: 1211-9
作者:
Christensen, Jesper
;
Litherland, Karine
;
Faller, Thomas
;
van de Kerkhof, Esther
;
Natt, François
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
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