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科研机构
上海药物研究所 [48]
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期刊论文 [48]
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2020 [3]
2018 [1]
2017 [1]
2016 [2]
2015 [3]
2013 [2]
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Pharmacolo... [2]
Chemistry [1]
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Alteration of twinfilin1 expression underlies opioid withdrawal-induced remodeling of actin cytoskeleton at synapses and formation of aversive memory
期刊论文
MOLECULAR PSYCHIATRY, 2021, 页码: 19
作者:
Wang, Yu-Jun
;
Yu, Chuan
;
Wu, Wei-Wei
;
Ju, Yun-Yue
;
Liu, Yao
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/06/11
Unveiling conformational dynamics changes of H-Ras induced by mutations based on accelerated molecular dynamics
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2020, 卷号: 22, 期号: 37, 页码: 21238-21250
作者:
Chen, Jianzhong
;
Wang, Wei
;
Pang, Laixue
;
Zhu, Weiliang
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/12/21
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:
Yuliantie, Elita
;
Darbalaei, Sanaz
;
Dai, Antao
;
Zhao, Peishen
;
Yang, Dehua
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
G protein-coupled receptor
Glucose-dependent insulinotropic peptide receptor
Glucagon-like peptide-1 receptor
Biased agonist
GPCR signaling
Effect of phosphatidylcholine on the stability and lipolysis of nanoemulsion drug delivery systems
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, 卷号: 583, 页码: 9
作者:
Zhang, Bo
;
Zhou, Xin
;
Miao, Yunqiu
;
Wang, Xiaoli
;
Yang, Yuting
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
Phosphatidylcholine
Nanoemulsion
Stability
Lipolysis kinetics
Curcumin
MOF Capacitates Cyclodextrin to Mega-Load Mode for High-Efficient Delivery of Valsartan
期刊论文
PHARMACEUTICAL RESEARCH, 2019, 卷号: 36, 期号: 8, 页码: 13
作者:
Zhang, Wei
;
Guo, Tao
;
Wang, Caifen
;
He, Yuanzhi
;
Zhang, Xi
收藏
  |  
浏览/下载:125/0
  |  
提交时间:2020/07/01
Bioavailability
cyclodextrin
metal-organic framework
solubility
valsartan
Cananga odorata essential oil reverses the anxiety induced by 1-(3-chlorophenyl) piperazine through regulating the MAPK pathway and serotonin system in mice
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 219, 页码: 23-30
作者:
Zhang, Nan
;
Zhang, Lei
;
Feng, Linyin
;
Yao, Lei
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
Cananga odorata
1-(3-Chlorophenyl) piperazine
Anxiolytic effect
MAPK
5-HT
Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1673-1682
作者:
Liu, Shi-en
;
Hu, Jun-chi
;
Zhang, Hao
;
Xu, Pan
;
Wan, Wei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
phosphoglycerate mutase 1 (PGAM1)
human cancers
metabolic target
C-terminal region
conformational changes
molecular dynamics simulation
The requirement of SEPT2 and SEPT7 for migration and invasion in human breast cancer via MEK/ERK activation
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 38, 页码: 61587-61600
作者:
Zhang, Nianzhu
;
Liu, Lu
;
Fan, Ning
;
Zhang, Qian
;
Wang, Weijie
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
septin
forchlorfenuron
breast cancer
invasion
MAPK
A pH-Responsive Host-guest Nanosystem Loading Succinobucol Suppresses Lung Metastasis of Breast Cancer
期刊论文
THERANOSTICS, 2016, 卷号: 6, 期号: 3, 页码: 435-445
作者:
Dan, Zhaoling
;
Cao, Haiqiang
;
He, Xinyu
;
Zhang, Zhiwen
;
Zou, Lili
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Host-guest nanosystem
pH-responsive
Cyclodextrin
Cancer metastasis
Breast cancer
Novel kappa-opioid receptor agonist MB-1C-OH produces potent analgesia with less depression and sedation
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 5, 页码: 565-571
作者:
Zhang, Le-sha
;
Wang, Jun
;
Chen, Jian-chun
;
Tao, Yi-min
;
Wang, Yu-hua
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
kappa-opioid receptor
MB-1C-OH
(-)U50,488H
Nor-BNI
morphine
pain
acetic acid-induced writhing
formalin test
depression
sedation
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