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科研机构
上海药物研究所 [9]
内容类型
期刊论文 [9]
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2021 [2]
2020 [1]
2018 [1]
2016 [1]
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2013 [2]
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Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation
期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:
Li, Heng
;
Zhang, Xianglei
;
Xiang, Caigui
;
Feng, Chunlan
;
Fan, Chen
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/11/04
PDE4
Arctigenin
Psoriasis
Inflammation
Activating Adenosine Monophosphate-Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice
期刊论文
HEPATOLOGY, 2021, 卷号: 73, 期号: 6, 页码: 2206-2222
作者:
Lin, Qian
;
Huang, Zhifeng
;
Cai, Genxiang
;
Fan, Xia
;
Yan, Xiaoqing
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/08/17
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
Structure and Physiological Regulation of AMPK
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 11
作者:
Yan, Yan
;
Zhou, X. Edward
;
Xu, H. Eric
;
Melcher, Karsten
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/01/08
energy metabolism
AMPK
activation loop
AID
-linker
-linker
CBS
LKB1
CaMKK2
RIM
Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 11, 页码: 1391-1400
作者:
Tao, Ling-xue
;
Huang, Xiao-tian
;
Chen, Yu-ting
;
Tang, Xi-can
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Alzheimer's disease
huperzine A
iron
reactive oxygen species
mitochondria dysfunction
acetylcholinesterase
Involvement of Intracellular and Mitochondrial A beta in the Ameliorative Effects of Huperzine A against Oligomeric A beta(42)-Induced Injury in Primary Rat Neurons
期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 5
作者:
Lei, Yun
;
Yang, Ling
;
Ye, Chun Yan
;
Qin, Ming Yan
;
Yang, Huai Yu
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Promising effects on ameliorating mitochondrial function and enhancing Akt signaling in SH-SY5Y cells by (M)-bicelaphanol A, a novel dimeric podocarpane type trinorditerpene isolated from Celastrus orbiculatus
期刊论文
PHYTOMEDICINE, 2013, 卷号: 20, 期号: 12, 页码: 1064-1070
作者:
Wang, Xu Jie
;
Wang, Luo Yi
;
Fu, Yan
;
Wu, Jian
;
Tang, Xi Can
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Celastrus orbiculatus
(M)-bicelaphanol A
Oxidative stress
Neurodegenerative disease
Hydrogen peroxide
Mitochondria
Apoptosis
Blocking A(2B) Adenosine Receptor Alleviates Pathogenesis of Experimental Autoimmune Encephalomyelitis via Inhibition of IL-6 Production and Th17 Differentiation
期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 190, 期号: 1, 页码: 138-146
作者:
Wei, Wei
;
Du, Changsheng
;
Lv, Jie
;
Zhao, Guixian
;
Li, Zhenxin
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Huperzine A protects isolated rat brain mitochondria against beta-amyloid peptide
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2009, 卷号: 46, 期号: 11, 页码: 1454-1462
作者:
Gao, Xin
;
Zheng, Chun Yan
;
Yang, Ling
;
Tang, Xi Can
;
Zhang, Hai Yan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Huperzine A
beta-Amyloid peptide
Mitochondria
Oxidative phosphorylation
Free radicals
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