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CORC

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Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 10, 页码: 4303-4318
作者:  Chen, Jianzhong;  Wang, Jinan;  Yin, Baohua;  Pang, Laixue;  Wang, Wei
收藏  |  浏览/下载：118/0  |  提交时间：2020/07/01
A pectin from fruits of Lycium barbarum L. decreases Beta-amyloid peptide production through modulating APP processing 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 201, 页码: 65-74
作者:  Zhou, Lishuang;  Liao, Wenfeng;  Zeng, Hui;  Yao, Yanli;  Chen, Xia
收藏  |  浏览/下载：159/0  |  提交时间：2019/01/08
Targeting the gamma-/beta-secretase interaction reduces beta-amyloid generation and ameliorates Alzheimer's disease-related pathogenesis 期刊论文
CELL DISCOVERY, 2015, 卷号: 1
作者:  Cui, Jin;  Wang, Xiaoyin;  Li, Xiaohang;  Wang, Xin;  Zhang, Chenlu
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
2,2',4'-Trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice 期刊论文
JOURNAL OF NEUROCHEMISTRY, 2010, 卷号: 114, 期号: 2, 页码: 374-385
作者:  Zhu, Zhiyuan;  Li, Chenjing;  Wang, Xu;  Yang, Zhengyi;  Chen, Jing
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08
Why does beta-secretase zymogen possess catalytic activity? Molecular modeling and molecular dynamics simulation studies 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2007, 卷号: 31, 期号: 3, 页码: 186-195
作者:  Zuo, Zhili;  Gang, Chen;  Zou, Hanjun;  Mok, Puah Chum;  Zhu, Weiliang
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Studies of secretase inhibitors of amyloid-ss protein 期刊论文
PROGRESS IN CHEMISTRY, 2004, 卷号: 16, 期号: 5, 页码: 791-796
作者:  Song, F;  He, XC;  Bai, DL
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08
Progress in beta-Secretase 期刊论文
Chemistry of Life, 2004, 卷号: 24, 期号: 2, 页码: 89-91
作者:  Ma Zeqiang;  Li Jingya;  Li Jia
收藏  |  浏览/下载：8/0  |  提交时间：2019/01/08

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