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科研机构
上海药物研究所 [21]
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期刊论文 [21]
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2021 [3]
2020 [1]
2018 [2]
2017 [2]
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2015 [3]
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A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11
作者:
Cheng, Zhiyang
;
Huang, Ying
;
Shen, Qianqian
;
Zhao, Yangrong
;
Wang, Lei
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2021/11/04
Cancer
beta-glucuronidase
Bioconjugation
Albumin
Camptothecin
A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation
期刊论文
LIFE SCIENCES, 2021, 卷号: 269, 页码: 8
作者:
Yang, Liu
;
Lei, Xian-Tao
;
Huang, Qi
;
Wang, Ting
;
Sun, Hong-Bin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
GPR120 agonist
Insulin secretion
Anti-inflammation
Insulin resistance
Type 2 diabetes mellitus
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:
Zhang, Rui
;
Li, Heng
;
Zhang, Xianglei
;
Li, Jian
;
Su, Haixia
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/24
PDE4 inhibitors
Tetrahydroisoquinoline
Antipsoriasis
Stepwise targeting and responsive lipid-coated nanoparticles for enhanced tumor cell sensitivity and hepatocellular carcinoma therapy
期刊论文
THERANOSTICS, 2020, 卷号: 10, 期号: 8, 页码: 3722-3736
作者:
Li, Ying
;
Miao, Yunqiu
;
Chen, Mingshu
;
Chen, Xi
;
Li, Feifei
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
drug delivery
pH sensitive
charge conversion
tumor targeting
hepatocellular carcinoma
Tumor Cells-Selective Bionic Nanodevice Exploiting Heparanase Combats Metastatic Breast Cancer
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2018, 卷号: 28, 期号: 17
作者:
Lang, Tianqun
;
Ran, Wei
;
Dong, Xinyue
;
Zheng, Zhong
;
Liu, Yiran
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
breast cancer
heparan sulfate
metastasis
red blood cell membranes
tumor-targeting micelles
Mesoporous silica nanoparticles for drug and gene delivery
期刊论文
Acta Pharmaceutica Sinica B, 2018, 卷号: 8, 期号: 2, 页码: 165
作者:
Zhou Yixian
;
Quan Guilan
;
Wu Qiaoli
;
Zhang Xiaoxu
;
Niu Boyi
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
Therapeutics. Pharmacology
RM1-950
Cancer Cell Membrane-Coated Gold Nanocages with Hyperthermia-Triggered Drug Release and Homotypic Target Inhibit Growth and Metastasis of Breast Cancer
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2017, 卷号: 27, 期号: 3
作者:
Sun, Huiping
;
Su, Jinghan
;
Meng, Qingshuo
;
Yin, Qi
;
Chen, Lingli
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
Dual pH-sensitive micelles with charge-switch for controlling cellular uptake and drug release to treat metastatic breast cancer
期刊论文
BIOMATERIALS, 2017, 卷号: 114, 页码: 44-53
作者:
Tang, Shan
;
Meng, Qingshuo
;
Sun, Huiping
;
Su, Jinghan
;
Yin, Qi
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Breast cancer
Charge-switch
Metastasis
Micelle
pH-sensitive
Sodium dodecyl sulfate/beta-cyclodextrin vesicles embedded in chitosan gel for insulin delivery with pH-selective release
期刊论文
ACTA PHARMACEUTICA SINICA B, 2016, 卷号: 6, 期号: 4, 页码: 344-351
作者:
Li, Zhuo
;
Li, Haiyan
;
Wang, Caifen
;
Xu, Jianghui
;
Singh, Vikramjeet
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Vesicles
beta-Cyclodexl
Insulin
Self-assembly
Gel
pH-selective release
The rapid antidepressant and anxiolytic-like effects of YY-21 involve enhancement of excitatory synaptic transmission via activation of mTOR signaling in the mPFC
期刊论文
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2016, 卷号: 26, 期号: 7, 页码: 1087-1098
作者:
Guo, Fei
;
Zhang, Bing
;
Fu, Zhiwen
;
Ma, Yuqin
;
Gao, Yu
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
YY-21
mTOR
Synaptic transmission
Synaptic proteins
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