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Computational Study on the Drug Resistance Mechanism against HCV NS3/4A Protease Inhibitors Vaniprevir and MK-5172 by the Combination Use of Molecular Dynamics Simulation, Residue Interaction Network, and Substrate Envelope Analysis 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2014, 卷号: 54, 期号: 2
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收藏  |  浏览/下载:3/0  |  提交时间:2014/12/05
Understanding the drug resistance mechanism of hepatitis C virus NS3/4A to ITMN-191 due to R155K, A156V, D168A/E mutations: A computational study 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2012, 卷号: 1820, 期号: 10, 页码: 1526-1534
作者:  Pan, DB;  Xue, WW;  Zhang, WQ;  Liu, HX;  Yao, XJ
收藏  |  浏览/下载:3/0  |  提交时间:2015/12/29
Molecular modeling study on the resistance mechanism of HCV NS3/4A serine protease mutants R155K, A156V and D168A to TMC435 期刊论文
ANTIVIRAL RESEARCH, 2012, 卷号: 93, 期号: 1
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