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上海药物研究所 [18]
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北京大学 [2]
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期刊论文 [33]
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Gut Microbiota in Adipose Tissue Dysfunction Induced Cardiovascular Disease: Role as a Metabolic Organ
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2021, 卷号: 12, 页码: 14
作者:
Yang, Xinyu
;
Zhang, Xianfeng
;
Yang, Wei
;
Yu, Hang
;
He, Qianyan
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/11/04
gut microbiota
adipose tissue dysfunction
molecular endocrinology
cardiovascular disease(s)
gut dysbiosis
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 9, 页码: 19
作者:
Xiong, Zhaoping
;
Jeon, Minji
;
Allaway, Robert J.
;
Kang, Jaewoo
;
Park, Donghyeon
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  |  
浏览/下载:24/0
  |  
提交时间:2021/11/04
SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:
Xia, Zong-jun
;
Ji, Yin-chun
;
Sun, De-qiao
;
Peng, Xia
;
Gao, Ying-lei
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  |  
浏览/下载:81/0
  |  
提交时间:2020/12/21
ROS1 kinase
ROS1 inhibitor
SAF-189s
lorlatinib
crizotinib resistance
G2032R mutant
NSCLC
BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFR(T790M) mutation
期刊论文
THERANOSTICS, 2020, 卷号: 10, 期号: 14, 页码: 6122-6135
作者:
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  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
brain targeting delivery
tumor-associated macrophage
non-small cell lung cancer (NSCLC)
drug resistance
tyrosine kinase inhibitors (TKI)
EGFR T790M mutation
Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models
期刊论文
CANCER LETTERS, 2019, 页码: 105-114
作者:
Lu, Tingting
;
Chen, Cheng
;
Wang, Aoli
;
Jiang, Zongru
;
Qi, Ziping
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  |  
浏览/下载:16/0
  |  
提交时间:2020/07/14
cKIT T670I mutant
Activation loop mutants
Drug resistance
Apoferritin nanocages loading mertansine enable effective eradiation of cancer stem-like cells in vitro
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2018, 卷号: 553, 期号: 1-2, 页码: 201-209
作者:
Tan, Tao
;
Wang, Yuqi
;
Wang, Hong
;
Cao, Haiqiang
;
Wang, Zhiwan
收藏
  |  
浏览/下载:141/0
  |  
提交时间:2019/01/08
Apoferritin
Mertansine
Cancer stem cells
Breast cancer
Nanocages
Drug delivery
Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFR(T790M)-Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery
期刊论文
SMALL, 2018, 卷号: 14, 期号: 47
作者:
Yin, Weimin
;
Yu, Xiaolu
;
Kang, Xuejia
;
Zhao, Yuge
;
Zhao, Pengfei
收藏
  |  
浏览/下载:105/0
  |  
提交时间:2019/01/08
antiangiogenesis
EGFR(T790M) mutation
PD-L1 nanobody
simvastatin
tumor-associated macrophage
High-risk screening and detection of multidrug-resistant tuberculosis in two prefectures of China: a drug susceptibility surveillance-based secondary data analysis
期刊论文
GLOBAL HEALTH ACTION, 2018, 卷号: 11, 期号: 1
作者:
Yang, Zhiqi
;
Zhou, Changming
;
Ning, Zhu
;
Lu, Wei
;
Zhao, Qi
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Tuberculosis
multidrug-resistance
screening strategy
high-risk groups
population attributable risk
Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527
作者:
Chen, Lingfeng
;
Fu, Weitao
;
Feng, Chen
;
Qu, Rong
;
Tong, Linjiang
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2019/01/08
Epidermal growth factor receptor
Tyrosine kinase inhibitors
Non-small cell lung cancer
T790M
Mutant-selective
Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review
期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11
作者:
Shah, Sayed Asmat Ali
;
Akhter, Najeeb
;
Auckloo, Bibi Nazia
;
Khan, Ishrat
;
Lu, Yanbin
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
cyanobacteria
secondary metabolites
biological properties and applications
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