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西北高原生物研究所 [27]
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期刊论文 [54]
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HINGRL: predicting drug-disease associations with graph representation learning on heterogeneous information networks
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-15
作者:
Zhao, BW (Zhao, Bo-Wei) [1] , [2]
;
Hu, L (Hu, Lun) [2]
;
You, ZH (You, Zhu-Hong) [3] , [4]
;
Wang, L (Wang, Lei) [5]
;
Su, XR (Su, Xiao-Rui) [1] , [2]
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/05/06
drug-disease associations
prediction
heterogeneous information network
graph representation learning
drug repositioning
MGRL: Predicting Drug-Disease Associations Based on Multi-Graph Representation Learning
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 4, 页码: 1-8
作者:
Zhao, BW (Zhao, Bo-Wei)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Wong, L (Wong, Leon)[ 1,2,3 ]
;
Zhang, P (Zhang, Ping)[ 4 ]
;
Li, HY (Li, Hao-Yuan)[ 5 ]
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  |  
浏览/下载:37/0
  |  
提交时间:2021/05/06
drug
disease
drug repositioning
multi-graph representation learning
graph embedding
In silico drug repositioning using deep learning and comprehensive similarity measures
期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 增刊3, 页码: 1-14
作者:
Yi, HC (Yi, Hai-Cheng) 1 , 2
;
You, ZH (You, Zhu-Hong) 1
;
Wang, L (Wang, Lei) 1
;
Su, XR (Su, Xiao-Rui) 1 , 2
;
Zhou, X (Zhou, Xi) 1
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/07/14
Drug repositioningDrug-disease interactionGated recurrent unitsGaussian interaction profile kernelMachine learning
Learning from low-rank multimodal representations for predicting disease-drug associations
期刊论文
BMC MEDICAL INFORMATICS AND DECISION MAKING, 2021, 卷号: 21, 期号: SUPPL1, 页码: 1-12
作者:
Hu, PW (Hu, Pengwei) [1]
;
Huang, YA (Huang, Yu-An) [2]
;
Mei, J (Mei, Jing) [3]
;
Leung, H (Leung, Henry) [4]
;
Chen, ZH (Chen, Zhan-Heng) [1]
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  |  
浏览/下载:14/0
  |  
提交时间:2022/03/24
Disease-drug associations predictionLow-rank tensorsMultimodal fusion
A Novel Method to Predict Drug-Target Interactions Based on Large-Scale Graph Representation Learning
期刊论文
CANCERS, 2021, 卷号: 13, 期号: 9, 页码: 1-12
作者:
Zhao, BW (Zhao, Bo-Wei) 1 , 2 , 3
;
You, ZH (You, Zhu-Hong) 1 , 2 , 3
;
Hu, L (Hu, Lun) 1 , 2 , 3
;
Guo, ZH (Guo, Zhen-Hao) 1 , 2 , 3
;
Wang, L (Wang, Lei) 1 , 2 , 3
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  |  
浏览/下载:36/0
  |  
提交时间:2021/07/27
drug discoverydrug-target interactionslarge-scale graph representation learningcomputational method
Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737
作者:
Li, Xutong
;
Li, Zhaojun
;
Wu, Xiaolong
;
Xiong, Zhaoping
;
Yang, Tianbiao
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  |  
浏览/下载:29/0
  |  
提交时间:2020/12/21
Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737
作者:
Li, Xutong
;
Li, Zhaojun
;
Wu, Xiaolong
;
Xiong, Zhaoping
;
Yang, Tianbiao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/21
SAEROF: an ensemble approach for large-scale drug-disease association prediction by incorporating rotation forest and sparse autoencoder deep neural network
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 1-11
作者:
Jiang, HJ (Jiang, Han-Jing)[ 1,2,3 ]
;
Huang, YA (Huang, Yu-An)[ 4 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/12/11
DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 17, 期号: 5, 页码: 478-495
作者:
Wan, Fangping
;
Zhu, Yue
;
Hu, Hailin
;
Dai, Antao
;
Cai, Xiaoqing
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
Deep learning
Machine learning
Drug discovery
In silico drug screening
Compound-protein interaction prediction
DrPOCS: Drug Repositioning Based on Projection Onto Convex Sets
期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2019, 卷号: 16, 期号: 1
作者:
Cui, Chunfeng
;
Zhao, Xing-Ming
;
Yan, Hong
;
Qi, Liqun
;
Wang, Yin-Ying
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/05
Drug repositioning
projection onto convex sets (POCS)
matrix completion
singular value decomposition (SVD)
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