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科研机构
上海药物研究所 [26]
内容类型
期刊论文 [26]
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2021 [3]
2020 [3]
2019 [6]
2018 [3]
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2015 [2]
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内容类型:期刊论文
专题:上海药物研究所
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Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
NaNbO3-(Bi0.5Li0.5)TiO3 Lead-Free Relaxor Ferroelectric Capacitors with Superior Energy-Storage Performances via Multiple Synergistic Design
期刊论文
ADVANCED ENERGY MATERIALS, 2021, 页码: 12
作者:
Xie, Aiwen
;
Zuo, Ruzhong
;
Qiao, Zhenliang
;
Fu, Zhengqian
;
Hu, Tengfei
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/08/17
energy-storage capacitors
lead-free relaxor ferroelectrics
multiscale structure evolution
nanodomains
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 13
作者:
Gao, Feng
;
Chen, Xiaoxu
;
Lu, Junyan
;
Hu, Shulei
;
Xu, Hui
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/05/24
Ceramide analogs
AKT inhibitor
MK2206
Colon cancer
Combination therapy
Engineering Prodrug Nanomedicine for Cancer Immunotherapy
期刊论文
ADVANCED SCIENCE, 2020, 页码: 33
作者:
Yang, Bin
;
Gao, Jing
;
Pei, Qing
;
Xu, Huixiong
;
Yu, Haijun
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/21
cancer immunotherapy
combination immunotherapy
nanomedicine
prodrugs
stimuli‐
responsive
BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis
期刊论文
THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12
作者:
Li, Guang
;
Zheng, Yan-Hua
;
Xu, Li
;
Feng, Juan
;
Tang, Hai-Long
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/12/24
apoptosis
BRD4 inhibitor
G1 phase cell cycle checkpoint
multiple myeloma
A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression
期刊论文
CANCER RESEARCH, 2020, 卷号: 80, 期号: 3, 页码: 536-548
作者:
Wang, Yingcong
;
Huang, Jing
;
Li, Bo
;
Xue, Han
;
Tricot, Guido
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
Enhancing Triple Negative Breast Cancer Immunotherapy by ICG-Templated Self-Assembly of Paclitaxel Nanoparticles
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2019, 页码: 13
作者:
Feng, Bing
;
Niu, Zifei
;
Hou, Bo
;
Zhou, Lei
;
Li, Yaping
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
immune checkpoint blockade
immunogenic cell death
immunotherapy
self-assemble
triple negative breast cancer
A comparative study of S center dot center dot center dot pi chalcogen bonds between SF2 or SFH and C-C multiple bonds
期刊论文
JOURNAL OF MOLECULAR STRUCTURE, 2019, 卷号: 1188, 页码: 62-68
作者:
Su, He
;
Wu, Han
;
Wang, Hui
;
Wang, Hongyan
;
Ni, Yuxiang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
Noncovalent chalcogen bond
First-principles
Molecular structure
Electronic properties
Energetic effects
Reprogramming Tumor Immune Microenvironment (TIME) and Metabolism via Biomimetic Targeting Codelivery of Shikonin/JQ1
期刊论文
NANO LETTERS, 2019, 卷号: 19, 期号: 5, 页码: 2935-2944
作者:
Wang, Hairui
;
Tang, Yisi
;
Fang, Yuefei
;
Zhang, Meng
;
Wang, Huiyuan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Biomimetic delivery
glucose metabolism
immunogenic cell death (ICD)
tumor-associated macrophage
shikonin
JQ1
DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2
期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 4797-4808
作者:
Kong, Yuanyuan
;
Li, Bo
;
Chang, Shuaikang
;
Gao, Lu
;
Xu, Zhijian
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
DCZ0814
multiple myeloma
mTOR
bone marrow microenvironment
apoptosis
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