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科研机构
北京大学 [53]
内容类型
期刊论文 [53]
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2017 [6]
2016 [5]
2015 [6]
2014 [2]
2013 [2]
2012 [5]
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内容类型:期刊论文
专题:北京大学
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Synthesis and evaluation of osimertinib derivatives as potent EGFR inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017
Gao, Hongying
;
Yang, Zimo
;
Yang, Xinglin
;
Rao, Yu
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2017/12/03
Osimertinib
N-Oxide metabolites
Fluoride
Non-small cell lung cancer
Epidermal growth factor receptor-tyrosine kinase inhibitors
CELL LUNG-CANCER
FACTOR RECEPTOR EGFR
MEDICINAL CHEMISTRY
TARGETED THERAPY
DRUG DISCOVERY
RESISTANCE
FLUORINE
MUTATIONS
MUTANT
PHARMACOKINETICS
Preparation, Characterization and In Vitro Biological Evaluation of Nano-Tubular Polyoxometalate
期刊论文
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2017
ul Hassan, Sadaf
;
Hasan, Murtaza
;
Firdous, Attia
;
Farid, Muhammad Asim
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
Solid Lipid Nano-Particles
Polyoxometalates Based Nanotubes
Pharmacokinetics
DRUG-DELIVERY
HPA-23
Preparation and evaluation of a novel anticancer drug delivery carrier for 5-Fluorouracil using synthetic bola-amphiphile based on lysine as polar heads
期刊论文
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2017
Hu, Beibei
;
Yuan, Yue
;
Yan, Yun
;
Zhou, Xiaoping
;
Li, Yue
;
Kan, Qiming
;
Li, Sanming
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
Bolaamphiphile
Self-assembly
pH-sensitive
Lysine
Cytotoxicity assay
FATTY-ACIDS
SURFACTANTS
VESICLES
BOLAAMPHIPHILES
MIXTURES
NIOSOMES
BEHAVIOR
SYSTEMS
Synthesis and biological evaluation of Aspergillomarasmine A derivatives as novel NDM-1 inhibitor to overcome antibiotics resistance
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017
Zhang, Jian
;
Wang, Sanshan
;
Wei, Qi
;
Guo, Qianqian
;
Bai, Yingjie
;
Yang, Shaoqiang
;
Song, Fuhang
;
Zhang, Lixin
;
Lei, Xiaoguang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
Aspergillomarasmine A
Antibiotic resistance
Metallo-beta-lactamases
NDM-1
Antibiotics
BETA-LACTAMASE INHIBITORS
BACTERIA
Monte Carlo simulation of Ray-Scan 64 PET system and performance evaluation using GATE toolkit
期刊论文
JOURNAL OF INSTRUMENTATION, 2017
Li, Suying
;
Zhang, Qiushi
;
Vuletic, Ivan
;
Xie, Zhaoheng
;
Yang, Kun
;
Ren, Qiushi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
Detector modelling and simulations I (interaction of radiation with matter, interaction of photons with matter, interaction of hadrons with matter, etc)
Gamma camera, SPECT, PET, PET/CT, coronary CT angiography (CTA)
Models and simulations
Simulation methods and programs
RECONSTRUCTION
PLATFORM
药物滥用人群传染病的疾病负担评估
期刊论文
中华医院感染学杂志, 2017
靳媛媛
;
李梦
;
刘天媛
;
金也平
;
陆祖宏
;
贾忠伟
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
药物滥用
传染病
期望寿命
患病率
成本
Drug abuse
Infectious disease
Life expectancy
Prevalence rate
Cost
A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells
期刊论文
PLOS ONE, 2016
Cao, Lili
;
Zhang, Lijun
;
Zhao, Xiang
;
Zhang, Ye
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2017/12/04
CANCER-CELLS
TUBULIN POLYMERIZATION
BIOLOGICAL EVALUATION
MUTATIONAL LANDSCAPE
MOLECULAR THERAPIES
ANTITUBULIN AGENTS
IN-VIVO
NUCLEOLIN
KINASE
IDENTIFICATION
Why does Togni's reagent I exist in the high-energy hypervalent iodine form? Re-evaluation of benziodoxole based hypervalent iodine reagents
期刊论文
CHEMICAL COMMUNICATIONS, 2016
Sun, Tian-Yu
;
Wang, Xiao
;
Geng, Hao
;
Xie, Yaoming
;
Wu, Yun-Dong
;
Zhang, Xinhao
;
Schaefer, Henry F., III
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2017/12/03
DENSITY-FUNCTIONAL THEORY
ELECTROPHILIC TRIFLUOROMETHYLATION
TRANS-INFLUENCE
CONCERTED MECHANISM
REACTIVITY
COMPLEXES
LIGANDS
DFT
ELECTRONEGATIVITY
ALKYNYLATION
Evaluation of synergistic enantioseparation systems with chiral spirocyclic ionic liquids as additives by capillary electrophoresis
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2016
Zhang, Yanjie
;
Du, Shuaijing
;
Feng, Zijie
;
Du, Yingxiang
;
Yan, Zhi
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2017/12/03
Chiral ionic liquids
Capillary electrophoresis
Enantiomeric separation
Synergistic system
Molecular modeling
GAS-CHROMATOGRAPHY
BETA-CYCLODEXTRIN
STATIONARY PHASES
SEPARATION
SELECTOR
ENANTIOSELECTIVITY
DRUGS
MEKC
CD
RECOGNITION
Peptide-conjugated PEGylated PAMAM as a highly affinitive nanocarrier towards HER2-overexpressing cancer cells
期刊论文
RSC ADVANCES, 2016
Rostami, Iman
;
Zhao, ZiJian
;
Wang, Zihua
;
Zhang, WeiKai
;
Zhong, Yeteng
;
Zeng, Qiang
;
Jia, XinRu
;
Hu, ZhiYuan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
ANTICANCER DRUG-DELIVERY
IN-VITRO EVALUATION
GENE DELIVERY
NANOPARTICLES
DOXORUBICIN
DENDRIMERS
LIPOSOMES
SYSTEM
TUMOR
LIGAND
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