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科研机构
上海药物研究所 [5]
心理研究所 [1]
海洋研究所 [1]
自动化研究所 [1]
内容类型
期刊论文 [8]
发表日期
2021 [8]
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An App knock-in rat model for Alzheimer's disease exhibiting A beta and tau pathologies, neuronal death and cognitive impairments
期刊论文
CELL RESEARCH, 2021, 页码: 19
作者:
Pang, Keliang
;
Jiang, Richeng
;
Zhang, Wei
;
Yang, Zhengyi
;
Li, Lin-Lin
收藏
  |  
浏览/下载:127/0
  |  
提交时间:2021/12/27
An App knock-in rat model for Alzheimer's disease exhibiting A beta and tau pathologies, neuronal death and cognitive impairments
期刊论文
CELL RESEARCH, 2021, 页码: 19
作者:
Pang, Keliang
;
Jiang, Richeng
;
Zhang, Wei
;
Yang, Zhengyi
;
Li, Lin-Lin
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/12/28
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
The Streptococcus agalactiae Ribose Binding Protein B (RbsB) Mediates Quorum Sensing Signal Uptake via Interaction with Autoinducer-2 Signals
期刊论文
JOURNAL OF OCEAN UNIVERSITY OF CHINA, 2021, 卷号: 20, 期号: 5, 页码: 1285-1295
作者:
Fan Bolin
;
Pan Lixia
;
Wang Zhongliang
;
Eakapol, Wangkahart
;
Huang Yuchong
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/09/18
Streptococcus agalactiae
RbsB protein
circular dichroism (CD) spectroscopy
isothermal titration calorimetry(200) (ITC200)
molecular docking
A systematic strategy integrating solid-phase extraction, full scan range splitting, mass defect filter and precursor ion list for comprehensive metabolite profiling of Danqi Tongmai tablet in rats
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 9
作者:
Li, Zhen-wei
;
Wei, Wen-long
;
Li, Hao-jv
;
Wu, Shi-fei
;
Huang, Yong
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/05/24
Metabolite profiling
Solid-phase extraction
Mass defect filter
Precursor ion list
Danqi Tongmai tablet
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Ren, Yu-ran
;
Ye, Yang-liang
;
Feng, Ying
;
Xu, Ti-fei
;
Shen, Yu
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
SL010110
gluconeogenesis
primary mouse hepatocytes
PEPCK1
acetylation
degradation
Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC-MS/MS
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 194, 页码: 10
作者:
Hu, Wenjuan
;
Chang, Lu
;
Ke, Changqiang
;
Xie, Yuanchao
;
Shen, Jingshan
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/05/24
Remdesivir
Nucleotide monophosphate
Nucleotide triphosphate
Stability
Recovery
LC-MS/MS
Novel Plasma miRNAs as Biomarkers and Therapeutic Targets of Alzheimer's Disease at the Prodromal Stage
期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2021, 卷号: 83, 期号: 2, 页码: 779-790
作者:
He, Haining
;
Liu, An
;
Zhang, Wei
;
Yang, Huanqing
;
Zhang, Minmin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/11/04
Alzheimer's disease
biomarkers
microRNAs
mild cognitive impairment
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