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合肥物质科学研究院 [32]
上海药物研究所 [24]
海洋研究所 [5]
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期刊论文 [82]
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2021 [82]
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Integrated genomic and DNA methylation analysis of patients with advanced non-small cell lung cancer with brain metastases
期刊论文
MOLECULAR BRAIN, 2021, 卷号: 14
作者:
Xu, Yanjun
;
Huang, Zhiyu
;
Yu, Xiaoqing
;
Chen, Kaiyan
;
Fan, Yun
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2022/01/25
Brain metastases
Predictive biomarker
DNA methylation
Somatic mutation
Advanced non-small cell lung cancer (advanced NSCLC)
From Classical Radiation to Modern Radiation: Past, Present, and Future of Radiation Mutation Breeding
期刊论文
FRONTIERS IN PUBLIC HEALTH, 2021, 卷号: 9
作者:
Ma, Liqiu
;
Kong, Fuquan
;
Sun, Kai
;
Wang, Ting
;
Guo, Tao
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/02/14
mutation breeding
classical radiation
particle radiation
space radiation
mutagenesis
Clinical outcomes of lung adenocarcinoma patients harboring uncommon epidermal growth factor receptor (EGFR) mutations treated with EGFR-tyrosine kinase inhibitors (TKIs)
期刊论文
ANNALS OF PALLIATIVE MEDICINE, 2021
作者:
Si, Jinfei
;
Gu, Xiaodong
;
Wang, Wenxian
;
Ying, Shenpeng
;
Song, Zhengbo
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2022/02/14
Epidermal growth factor receptor (EGFR)
uncommon mutation
compound mutation
double uncommon mutation
lung adenocarcinoma (lung AC)
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
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  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
p53 Immunohistochemistry Patterns Are Surrogate Biomarkers for TP53 Mutations in Gastrointestinal Neuroendocrine Neoplasms
期刊论文
GASTROENTEROLOGY RESEARCH AND PRACTICE, 2021, 卷号: 2021
作者:
Li, Junjie
;
Wang, Jing
;
Su, Dan
;
Nie, Xiu
;
Liu, Yueping
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  |  
浏览/下载:50/0
  |  
提交时间:2022/02/14
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Li, Teng-teng
;
Peng, Cheng
;
Wang, Ji-qiu
;
Xu, Zhi-jian
;
Su, Ming-bo
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  |  
浏览/下载:42/0
  |  
提交时间:2022/01/18
DPP4
distal mutation
enzymatic activity
molecular dynamics simulation
structure-function mechanism
Genome Editing in the Olive Flounder (Paralichthys olivaceus) Using CRISPR/Cas9 and a Simple Microinjection System
期刊论文
JOURNAL OF OCEAN UNIVERSITY OF CHINA, 2021, 卷号: 20, 期号: 6, 页码: 1528-1536
作者:
Tan Xungang
;
Wang Ling
;
Wu Zhihao
;
Jiao Shuang
;
Wang Lijuan
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/01/05
CRISPR
Cas9
gsdf
microinjection
myomaker
needle with brake
olive flounder
State of the phycobilisome determines effective absorption cross-section of Photosystem II in Synechocystis sp. PCC 6803
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2021, 卷号: 1862, 期号: 12, 页码: 11
作者:
Protasova, Elena A.
;
Antal, Taras K.
;
Zlenko, Dmitry, V
;
Elanskaya, Irina, V
;
Lukashev, Evgeny P.
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/06/16
Nitrogen starvation
Phycobiliproteins
Photosystem II
Orange Carotenoid Protein
An App knock-in rat model for Alzheimer's disease exhibiting A beta and tau pathologies, neuronal death and cognitive impairments
期刊论文
CELL RESEARCH, 2021, 页码: 19
作者:
Pang, Keliang
;
Jiang, Richeng
;
Zhang, Wei
;
Yang, Zhengyi
;
Li, Lin-Lin
收藏
  |  
浏览/下载:110/0
  |  
提交时间:2021/12/27
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
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