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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 发表日期：2021     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Ropivacaine suppresses tumor biological characteristics of human hepatocellular carcinoma via inhibiting IGF-1R/PI3K/AKT/mTOR signaling axis 期刊论文 BIOENGINEERED, 2021, 卷号: 12 作者:  Zhang, Runze;  Lian, Yanhong;  Xie, Kangjie;  Cai, Yunfang;  Pan, Yafei 收藏  |  浏览/下载：40/0  |  提交时间：2022/01/10 Ropivacaine  hepatocellular carcinoma  IGF-1R  IGF1R-PI3K-AKT-mTOR signaling  cell cycle  epithelial-mesenchymal transition   Role of FUS-CHOP in Myxoid Liposarcoma via miR-486/CDK4 Axis 期刊论文 BIOCHEMICAL GENETICS, 2021 作者:  Wu, Hao;  Xia, Liming;  Xu, Haichao 收藏  |  浏览/下载：40/0  |  提交时间：2022/01/10 FUS-CHOP  Myxoid liposarcoma  Apoptosis  miR-486  CDK4 axis   Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847 作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing 收藏  |  浏览/下载：32/0  |  提交时间：2021/12/16 Protein degradation technology: a strategic paradigm shift in drug discovery 期刊论文 JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 卷号: 14 作者:  Li, Haobin;  Dong, Jinyun;  Cai, Maohua;  Xu, Zhiyuan;  Cheng, Xiang-Dong 收藏  |  浏览/下载：33/0  |  提交时间：2021/11/01 Protein degradation  Degradation pathway  Degradation technology  PROTAC  Monomeric degraders   Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition 期刊论文 CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 6, 页码: 1929-1936 作者:  Gao, Jing;  Zhang, Hanwu;  Zhou, Fengqi;  Hou, Bo;  Chen, Meiwan 收藏  |  浏览/下载：17/0  |  提交时间：2021/08/17 Cancer immunotherapy  siRNA delivery  Acid-activatible micelleplex  CDK4  6 inhibitor  PD-L1 knockdown   Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway 期刊论文 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583 作者:  Hu, Ke;  Li, Bo;  Ma, Ruye;  Yi, Hongfei;  Xu, Zhijian 收藏  |  浏览/下载：71/0  |  提交时间：2021/06/11 caspase  cell proliferation  cell cycle arrest  diffuse large B-cell lymphoma  PI3K-AKT-mTOR/JNK pathway   Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 12 作者:  Lin, Tingting;  Li, Jiacheng;  Liu, Liping;  Li, Yuanqing;  Jiang, Hualiang 收藏  |  浏览/下载：73/0  |  提交时间：2021/05/24 CDK2 inhibitor  Selectivity  Anti-proliferative potency   Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury 期刊论文 CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 7, 页码: 925-941 作者:  Liu, Yanjun;  Li, Jiacheng;  Liao, Liping;  Huang, Heming;  Fan, Shijie 收藏  |  浏览/下载：21/0  |  提交时间：2021/08/17 Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11 作者:  Qiu, Xiaqiu;  Li, Yuanqing;  Yu, Bin;  Ren, Jie;  Huang, Huidan 收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24 CDK9  Antitumor  PROTAC  AML  Degrader   Multiple functions of p21 in cancer radiotherapy 期刊论文 JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021, 页码: 20 作者:  Kuang, Yanbei;  Kang, Jian;  Li, Hongbin;  Liu, Bingtao;  Zhao, Xueshan 收藏  |  浏览/下载：16/0  |  提交时间：2021/12/10 p21  Cell cycle  Apoptosis  DNA damage repair  Cancer radiotherapy