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浏览/检索结果: 共22条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Dong, Ying;  Tang, Bi-xi;  Wang, Qi;  Zhou, Li-wei;  Li, Cong 收藏  |  浏览/下载：79/0  |  提交时间：2022/01/04 idiopathic pulmonary fibrosis  DDRs  kinase inhibitor  indazole derivatives  XBLJ-13  nintedanib  bleomycin-induced pulmonary fibrosismouse model   GADD45 beta stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation 期刊论文 PHARMACOLOGICAL RESEARCH, 2021, 卷号: 173, 页码: 11 作者:  Dong, Yunxia;  Ma, Ningning;  Fan, Lei;  Yuan, Luyang;  Wu, Qian 收藏  |  浏览/下载：61/0  |  提交时间：2021/12/16 Non-alcoholic fatty liver disease  GADD45 beta  HSP72  Lipid accumulation  Insulin resistance   Structural characteristics of Heparan sulfate required for the binding with the virus processing Enzyme Furin 期刊论文 GLYCOCONJUGATE JOURNAL, 2021, 页码: 11 作者:  Zeng, Jiaxin;  Meng, Yuan;  Chen, Shi-Yi;  Zhao, Gaofeng;  Wang, Lianchun 收藏  |  浏览/下载：53/0  |  提交时间：2021/12/01 Furin  Heparan sulfate  Heparin  Virus infection  Carbohydrate-protein interaction   5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19 作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing 收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04 NSD2  Methyltransferase  HTS  Multiple myeloma  5-Aminonaphthalene derivatives  Inhibitor   PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery 期刊论文 AUTOPHAGY, 2021, 卷号: 17, 期号: 10, 页码: 2905-2922 作者:  Tang, Ying;  Liu, Jinchang;  Wang, Yu;  Yang, Li;  Han, Bing 收藏  |  浏览/下载：46/0  |  提交时间：2022/01/04 Autophagy  functional recovery  ischemic stroke  lysophosphatidic acid receptor 5  microglial activation  poly (ADP-ribose) polymerase 14   Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK 期刊论文 CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263 作者:  Elksnis, Andris;  Schiffer, Tomas A.;  Palm, Fredrik;  Wang, Yun;  Cen, Jing 收藏  |  浏览/下载：22/0  |  提交时间：2021/12/01 Design and Synthesis of Alkyl Phenols Inhibitors of Death Associated Apoptotic Protein Kinase 2 (DRAK2) 期刊论文 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3204-3213 作者:  Zheng Zhang;  Dai Chengqiu;  Wu Honghong;  Li Jingya;  Nan Fajun 收藏  |  浏览/下载：20/0  |  提交时间：2021/11/04 death associated apoptotic protein kinase 2  diabetes  alkylphenols  inhibitors   HBO1 is a versatile histone acyltransferase critical for promoter histone acylations 期刊论文 NUCLEIC ACIDS RESEARCH, 2021, 卷号: 49, 期号: 14, 页码: 8037-8059 作者:   收藏  |  浏览/下载：75/0  |  提交时间：2021/11/04 Ketamine activated glutamatergic neurotransmission by GABAergic disinhibition in the medial prefrontal cortex 期刊论文 NEUROPHARMACOLOGY, 2021, 卷号: 194, 页码: 10 作者:  Zhang, Bing;  Yang, Xili;  Ye, Luyu;  Liu, Rui;  Ye, Binglu 收藏  |  浏览/下载：20/0  |  提交时间：2021/08/17 Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15 作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua 收藏  |  浏览/下载：36/0  |  提交时间：2021/11/04