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科研机构
上海药物研究所 [7]
兰州理工大学 [2]
过程工程研究所 [1]
生态环境研究中心 [1]
内容类型
期刊论文 [10]
学位论文 [1]
发表日期
2020 [11]
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Clinical application of pyrrole-hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans
期刊论文
ARCHIVES OF TOXICOLOGY, 2020, 页码: 7
作者:
Ma, Jiang
;
Zhang, Wei
;
He, Yisheng
;
Zhu, Lin
;
Zhang, Chunyuan
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/12/24
Pyrrolizidine alkaloids
Liver injury
Diagnostic biomarkers
Pyrrole-hemoglobin adducts
Pyrrole-plasma protein adducts
Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 6
作者:
Hu, Wen-juan
;
Chang, Lu
;
Yang, Ying
;
Wang, Xin
;
Xie, Yuan-chao
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/12/21
remdesivir
pharmacokinetics
tissue distribution
nucleotide monophosphate
nucleotide triphosphate
nucleoside
Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 9
作者:
Qiu, Yanan
;
Tang, Chongzhuang
;
Li, Ranran
;
Cao, Sumin
;
Zhang, Yuqiang
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/24
LC-MS
MS
N-oxide
stability
sutetinib
DGAT1 inhibitors protect pancreatic beta-cells from palmitic acid-induced apoptosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Huang, Jun-shang
;
Guo, Bin-bin
;
Wang, Gai-hong
;
Zeng, Li-min
;
Hu, You-hong
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/12/24
type 2 diabetes
DGAT1 inhibitors
pancreatic beta-cells
apoptosis
ER stress
inflammation
帕金森病靶向输递体系用于基因-化药协同治疗的研究
学位论文
: 中国科学院大学, 2020
作者:
刘霖颖
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  |  
浏览/下载:28/0
  |  
提交时间:2021/09/07
帕金森病,Sirna,联合递送,仿生设计
Optimization and mechanism of postponing aging of polysaccharides from Chinese herbal medicine formula
期刊论文
TOXICOLOGY RESEARCH, 2020, 卷号: 9, 期号: 3, 页码: 239-248
作者:
Pu, Xiuying
;
Luo, Amiao
;
Su, Hui
;
Zhang, Kaili
;
Tian, Changyi
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/03/01
polysaccharide
optimization
orthogonal design
anti-aging
D-galactose
aging rats
mechanism
A proton-coupled organic cation antiporter is involved in the blood-brain barrier transport of Aconitum alkaloids
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 252, 页码: 9
作者:
Cong, Jiaojiao
;
Ruan, Yiling
;
Lyu, Qinglin
;
Qin, Xiaohui
;
Qi, Xinming
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Aconitum alkaloids
Blood-brain barrier
Proton-coupled organic cation antiporter
hCMEC/D3 cells
Drug transport
The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor
期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 45, 期号: 1, 页码: 15-26
作者:
Zhang, Leduo
;
Mao, Yu
;
Gao, Zhiwei
;
Chen, Xiaoyan
;
Li, Xin
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  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Preparation and evaluation of PEGylated asiatic acid nanostructured lipid carriers on anti-fibrosis effects
期刊论文
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2020, 卷号: 46, 期号: 1, 页码: 57-69
作者:
Chen, Xiaoxiao
;
Zhang, Yawen
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
Asiatic acid
PEGylated nanostructured lipid carriers
anti-liver fibrosis
liver targeting strategy
pharmacokinetics
Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting
期刊论文
THERANOSTICS, 2020, 卷号: 10, 期号: 14, 页码: 6384-6398
作者:
Ren, Liting
;
Feng, Wenya
;
Shao, Jie
;
Ma, Juan
;
Xu, Ming
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/09/14
diethyldithiocarbamate
DSF-Cu nanocomplex
light-triggered nuclear targeting
metastasis
epithelial-mesenchymal transition
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