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科研机构
上海药物研究所 [12]
近代物理研究所 [2]
西北高原生物研究所 [1]
海洋研究所 [1]
生态环境研究中心 [1]
内容类型
期刊论文 [17]
发表日期
2020 [17]
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Seasonal variations of eddy kinetic energy flux in the South Indian Countercurrent region
期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 卷号: 38, 期号: 5, 页码: 1464-1475
作者:
Chen Zhongqian
;
Wang Faming
;
Zheng Jian
;
Yang Yuxing
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/04/12
mesoscale eddies
spectral kinetic energy flux
inverse cascade
South Indian Countercurrent (SICC)
Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 16, 页码: 6
作者:
Su, Zhicheng
;
Yang, Tingyuan
;
Wang, Jie
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
EGFR
NSCLC
C797S
Corn silk crude polysaccharide exerts anti-pancreatic cancer activity by blocking the EGFR/PI3K/AKT/CREB signaling pathway
期刊论文
FOOD & FUNCTION, 2020, 卷号: 11, 期号: 8, 页码: 6961-6970
作者:
Tao, Hong
;
Chen, Xia
;
Du, Zhenyun
;
Ding, Kan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
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  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe
期刊论文
Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1
作者:
Hu,Liangning
;
Li,Bo
;
Chen,Gege
;
Song,Dongliang
;
Xu,Zhijian
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  |  
浏览/下载:95/0
  |  
提交时间:2020/07/01
Multiple myeloma
Drug-resistance
DNA damage response
Cell cycle
A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction
期刊论文
INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713
作者:
Damaneh, Mohammadali Soleimani
;
Hu, Jian-Ping
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Tian, Chang-Qing
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
BET inhibitor
Cell proliferation
Apoptosis
Anti-cancer agent
BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis
期刊论文
THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12
作者:
Li, Guang
;
Zheng, Yan-Hua
;
Xu, Li
;
Feng, Juan
;
Tang, Hai-Long
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/12/24
apoptosis
BRD4 inhibitor
G1 phase cell cycle checkpoint
multiple myeloma
LncRNA UCA1 Antagonizes Arsenic-Induced Cell Cycle Arrest through Destabilizing EZH2 and Facilitating NFATc2 Expression
期刊论文
ADVANCED SCIENCE, 2020, 卷号: 7, 期号: 11, 页码: 1-16
作者:
Dong, Zheng
;
Gao, Ming
;
Li, Changying
;
Xu, Ming
;
Liu, Sijin
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/09/14
arsenic
cell cycle arrest
enhancer of zeste homolog 2 (EZH2)
lncRNA
tumorigenesis
urothelial cancer associated 1 (UCA1)
A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib
期刊论文
CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55
作者:
Chen, Gege
;
Hu, Ke
;
Sun, Haiguo
;
Zhou, Jinfeng
;
Song, Dongliang
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2020/07/01
Multiple myeloma
Bone marrow microenvironment
DNA damage
JAK2/STAT3 pathway
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Chen, Xiang-ling
;
Liu, Peng
;
Zhu, Wei-liang
;
Lou, Li-guang
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/07/01
DCZ5248
Hsp90
autophagy
lysosomal function
antitumor activity
colon cancer
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