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上海药物研究所 [9]
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期刊论文 [17]
发表日期
2020 [17]
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Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15153-15186
作者:
Zheng, Wei
;
Wang, Zhen
;
Jiang, Xiangrui
;
Zhao, Qingjie
;
Shen, Jingshan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Zheng, Yuan-dong
;
Zhang, Hua
;
Zhan, Yan
;
Bian, Yi-cong
;
Ma, Sheng
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
vicagrel
[C-14]vicagrel
vicagrel pharmacokinetics
vicagrel metabolism
mass balance
P2Y(12) receptor inhibitor
Direct quantification of anorethidrani disuccinate and determination of sterol metabolites by chemical derivatization combined with LC-MS/MS: Application to a Phase I pharmacokinetic study in humans
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1157, 页码: 9
作者:
Jiang, Jinfang
;
Li, Liang
;
Lu, Youming
;
Chen, Yunhui
;
Chen, Xiaoyan
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  |  
浏览/下载:44/0
  |  
提交时间:2020/12/24
Anorethidrani disuccinate
ACP
Sterol metabolite
Glycidyl trimethyl ammonium chloride
LC-MS/MS
A rank-based approach to estimating monotone individualized two treatment regimes
期刊论文
COMPUTATIONAL STATISTICS & DATA ANALYSIS, 2020, 卷号: 151, 页码: 12
作者:
Zhang, Haixiang
;
Huang, Jian
;
Sun, Liuquan
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  |  
浏览/下载:32/0
  |  
提交时间:2020/09/23
Generalized regression
Individualized treatment rule
Outlier
Personalized medicine
Rank correlation
Sex-differential associations between cognitive impairments and white matter abnormalities in first episode and drug-naive schizophrenia
期刊论文
EARLY INTERVENTION IN PSYCHIATRY, 2020, 页码: 9
作者:
Yang, Mi
;
Gao, Shan
;
Xiong, Weisen
;
Zhang, Xiang Yang
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  |  
浏览/下载:19/0
  |  
提交时间:2020/11/30
cognitive impairment
first episode
schizophrenia
sex difference
white matter
Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 180, 页码: 16
作者:
Darbalaei, Sanaz
;
Yuliantie, Elita
;
Dai, Antao
;
Chang, Rulue
;
Zhao, Peishen
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/21
G protein-coupled receptor
Glucagon-like peptide-1 receptor
Glucagon receptor
Biased agonism
Unimolecular dual agonist
Best (but oft-forgotten) practices: sample size and power calculation for a dietary intervention trial with episodically consumed foods
期刊论文
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2020, 卷号: 112, 期号: 4, 页码: 920-925
作者:
Zhang, Wei
;
Liu, Aiyi
;
Zhang, Zhiwei
;
Nansel, Tonja
;
Halabi, Susan
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  |  
浏览/下载:10/0
  |  
提交时间:2021/01/14
dietary intervention trials
episodic consumption
power
sample size
type I error
A phase II randomized trial of sodium oligomannate in Alzheimer's dementia
期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2020, 卷号: 12, 期号: 1, 页码: 10
作者:
Wang, Tao
;
Kuang, Weihong
;
Chen, Wei
;
Xu, Wenwei
;
Zhang, Liming
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2020/12/21
Sodium oligomannate
Efficacy
Safety
Alzheimer's disease
Clinical trial
Repurposing of Kinase Inhibitors for Treatment of COVID-19
期刊论文
PHARMACEUTICAL RESEARCH, 2020, 卷号: 37
作者:
Weisberg, Ellen
;
Parent, Alexander
;
Yang, Priscilla L.
;
Sattler, Martin
;
Liu, Qingsong
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/10/26
Coronavirus
SARS-CoV-2
SARS-CoV
MERS-CoV
kinase inhibitors
pharmacokinetics
antiviral therapy
COVID-19
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:
Yuliantie, Elita
;
Darbalaei, Sanaz
;
Dai, Antao
;
Zhao, Peishen
;
Yang, Dehua
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
G protein-coupled receptor
Glucose-dependent insulinotropic peptide receptor
Glucagon-like peptide-1 receptor
Biased agonist
GPCR signaling
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