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科研机构
上海药物研究所 [11]
内容类型
期刊论文 [11]
发表日期
2020 [11]
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发表日期:2020
专题:上海药物研究所
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Repeated Nitrous Oxide Exposure Exerts Antidepressant-Like Effects Through Neuronal Nitric Oxide Synthase Activation in the Medial Prefrontal Cortex
期刊论文
FRONTIERS IN PSYCHIATRY, 2020, 卷号: 11, 页码: 11
作者:
Liu, Wei
;
Li, Qian
;
Ye, Binglu
;
Cao, Hang
;
Shen, Fuyi
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/12/21
nitrous oxide (N2O)
depression
mPFC
burst firing
neuronal nitric oxide synthase (nNOS)
BDNF
Repeated Nitrous Oxide Exposure Exerts Antidepressant-Like Effects Through Neuronal Nitric Oxide Synthase Activation in the Medial Prefrontal Cortex
期刊论文
FRONTIERS IN PSYCHIATRY, 2020, 卷号: 11, 页码: 11
作者:
Liu, Wei
;
Li, Qian
;
Ye, Binglu
;
Cao, Hang
;
Shen, Fuyi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
nitrous oxide (N2O)
depression
mPFC
burst firing
neuronal nitric oxide synthase (nNOS)
BDNF
Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 16, 页码: 6
作者:
Su, Zhicheng
;
Yang, Tingyuan
;
Wang, Jie
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
EGFR
NSCLC
C797S
Whole-genome sequence of Phellinus gilvus (mulberry Sanghuang) reveals its unique medicinal values
期刊论文
JOURNAL OF ADVANCED RESEARCH, 2020, 卷号: 24, 页码: 325-335
作者:
Huo, Jinxi
;
Zhong, Shi
;
Du, Xin
;
Cao, Yinglong
;
Wang, Wenqiong
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2020/12/24
Anti-carcinogenesis activity
Genome sequencing
HR-ESI-MS
Inoscavin A
Phellinus gilvus
Phenylpropanoids biosynthesis
Design, synthesis and antiproliferative activity evaluation of a series of pyrrolo [2,1-f] [1,2,4] triazine derivatives
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 12, 页码: 4
作者:
Xiang, Hao-Yue
;
Chen, Yan-Hong
;
Wang, Yi
;
Zhang, Xi
;
Ding, Jian
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Antiproliferative
Cancer
Therapy
PI3K inhibitors
Pyrrolo [2,1-f][1,2,4] triazine
Kinase
Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5
作者:
Satheeshkumar, Rajendran
;
Zhu, Rui
;
Feng, Bo
;
Huang, Chao
;
Gao, Ya
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Heterocyclic bis-aryl amides
PTP1B
SHP2
Inhibitors
Structure-activity relationships (SAR)
Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14
作者:
Zhang, Xin
;
Xu, Fang
;
Tong, Linjiang
;
Zhang, Tao
;
Xie, Hua
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/07/01
Epidermal growth factor receptor (EGFR)
Resistance
Proteolysis targeting chimera (PROTAC)
Protein degradation
Synthesis of triazolotriazine derivatives as c-Met inhibitors
期刊论文
MOLECULAR DIVERSITY, 2020, 页码: 8
作者:
Guo, Yuting
;
Peng, Xia
;
Ji, Yinchun
;
Zhang, Yitong
;
Ding, Jian
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/24
Receptor tyrosine kinase
c-Met
Triazolotriazine
SAR
Cellular potency
Design, synthesis, and biological evaluation of 1,2,5-oxadiazole-3-carboximidamide derivatives as novel indoleamine-2,3-dioxygenase 1 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 189, 页码: 14
作者:
Song, Xiaohan
;
Sun, Pu
;
Wang, Jiang
;
Guo, Wei
;
Wang, Yi
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
IDO1 inhibitors
Immunotherapy
Anti-Tumor
Design, synthesis and biological evaluation of vincamine derivatives as potential pancreatic beta-cells protective agents for the treatment of type 2 diabetes mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 188, 页码: 17
作者:
Wang, Junwei
;
Lv, Xue
;
Xu, Jiawen
;
Liu, Xinpeng
;
Du, Te
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Type 2 diabetes mellitus
Pancreatic beta-cells protective agents
Vincamine derivatives
Structural modifications
Structure-activity relationships
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