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浏览/检索结果: 共18条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15399-15409 作者:  Chen, Lin-Hai;  Zhang, Qing;  Xie, Xin;  Nan, Fa-Jun 收藏  |  浏览/下载：18/0  |  提交时间：2021/05/24 A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor 期刊论文 CELL RESEARCH, 2020, 页码: 11 作者:  Sun, Wen;  Chen, Li-Nan;  Zhou, Qingtong;  Zhao, Li-Hua;  Yang, Dehua 收藏  |  浏览/下载：88/0  |  提交时间：2020/12/24 SARS-CoV-2 and Three Related Coronaviruses Utilize Multipke ACE2 Orthologs and Are Potently Blocked by an Improved ACE2-Ig 期刊论文 JOURNAL OF VIROLOGY, 2020, 卷号: 94, 期号: 22, 页码: 14 作者:  Li, Yujun;  Wang, Haimin;  Tang, Xiaojuan;  Fang, Shisong;  Ma, Danting 收藏  |  浏览/下载：25/0  |  提交时间：2020/12/21 ACE2  ACE2-Ig  SARS-CoV-2  entry inhibitor  host range   DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation 期刊论文 BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69 作者:  Lv, Jianlu;  Wang, Wei;  Zhu, Xialin;  Xu, Xiaoju;  Yan, Qiuying 收藏  |  浏览/下载：33/0  |  提交时间：2020/12/21 Alzheimer'sdisease  Microglia  AMPK alpha 1  DW14006  Phagocytosis  Neuro-inflammation   Design of G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) soft drugs with reduced gallbladder-filling effects 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 12 作者:  Han, Fanghui;  Ning, Mengmeng;  Cao, Hua;  Ye, Yangliang;  Feng, Ying 收藏  |  浏览/下载：34/0  |  提交时间：2020/12/21 Soft drug  TGR5  GLP-1  Gallbladder-filling effects  Rapid metabolism  Carboxylic ester   Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors 期刊论文 BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 180, 页码: 16 作者:  Darbalaei, Sanaz;  Yuliantie, Elita;  Dai, Antao;  Chang, Rulue;  Zhao, Peishen 收藏  |  浏览/下载：19/0  |  提交时间：2020/12/21 G protein-coupled receptor  Glucagon-like peptide-1 receptor  Glucagon receptor  Biased agonism  Unimolecular dual agonist   The triterpenoid sapogenin (2 alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling 期刊论文 CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 9, 页码: 10 作者:  Xie, Zhifu;  Jiang, Haowen;  Liu, Wei;  Zhang, Xinwen;  Chen, Dakai 收藏  |  浏览/下载：38/0  |  提交时间：2020/12/21 The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Yang, Fang-ming;  Fan, Di;  Yang, Xiao-qian;  Zhu, Feng-hua;  Shao, Mei-juan 收藏  |  浏览/下载：28/0  |  提交时间：2020/12/24 dry eye disease  artemisinin derivative  beta-aminoarteether maleate  inflammation  macrophages  TLR4  inflammasome   Structural insights into the activation of GLP-1R by a small molecule agonist 期刊论文 CELL RESEARCH, 2020, 页码: 3 作者:  Ma, Honglei;  Huang, Wei;  Wang, Xiaoxi;  Zhao, Lihua;  Jiang, Yi 收藏  |  浏览/下载：41/0  |  提交时间：2020/12/24 Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide 期刊论文 JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325 作者:  Chang, Rulue;  Zhang, Xin;  Qiao, Anna;  Dai, Antao;  Belousoff, Matthew J. 收藏  |  浏览/下载：89/0  |  提交时间：2020/12/24 glucagon receptor  glucagon-like peptide-1 receptor  dual agonist  cryo-electron microscopy  single particle analysis  structure-function  structural biology  peptide 15 (P15)  metabolic disorder  G protein?coupled receptor (GPCR)  glucagon  GLP-1 receptor