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上海药物研究所 [22]
合肥物质科学研究院 [9]
生态环境研究中心 [6]
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期刊论文 [58]
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2020 [58]
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发表日期:2020
内容类型:期刊论文
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Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298
作者:
Ding, Chunyong
;
Song, Zilan
;
Shen, Ancheng
;
Chen, Tingting
;
Zhang, Ao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Immunotherapy
Anti-tumor
cGAS
STING
TBK1
Small molecule modulators
Carbon Ion Therapy Inhibits Esophageal Squamous Cell Carcinoma Metastasis by Upregulating STAT3 Through the JAK2/STAT3 Signaling Pathway
期刊论文
FRONTIERS IN PUBLIC HEALTH, 2020, 卷号: 8, 页码: 11
作者:
Luo, Hongtao
;
Yang, Zhen
;
Zhang, Qiuning
;
Shao, Lihua
;
Wei, Shihong
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/12/13
carbon ion beam
esophageal squamous cell carcinoma
apoptosis
metastasis
JAK2
STAT3 pathway
Non-thermal plasma induces apoptosis accompanied by protective autophagy via activating JNK/Sestrin2 pathway
期刊论文
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2020, 卷号: 53
作者:
Ma, Jie
;
Yu, K. N.
;
Zhang, Hao
;
Nie, Lili
;
Cheng, Cheng
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2020/10/28
non-thermal plasma
apoptosis
protective autophagy
c-JUN N-terminal kinase
Sestrin2
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway
期刊论文
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:
Liu, Siwen
;
Huang, Suling
;
Wu, Xingde
;
Feng, Ying
;
Shen, Yu
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/12/24
Salt-inducible kinase 1
Phanginin A
Phosphodiesterase 4
Gluconeogenesis
cAMP
Oxidative damage mechanism in Saccharomyces cerevisiae cells exposed to tetrachlorobisphenol A
期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2020, 卷号: 80, 页码: 1-8
作者:
Zhang, Xiaoru
;
Zhang, Yaxian
;
Ji, Zhihua
;
Wang, Fengbang
;
Zhang, Lei
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/09/14
Tetrachlorobisphenol A
Reactive oxygen species accumulation
Signaling pathway
Saccharomyces cerevisiae
The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39
作者:
Ma, Liying
;
Bian, Xing
;
Lin, Wenchu
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/11/30
SCLC
PI3K
HDAC
CUDC-907
PARP1
Olaparib
DSB repair
Combination treatment
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 404, 页码: 14
作者:
Wang, Ying
;
Zhu, Yao
;
Niu, Junxing
;
Deng, Qiangqiang
;
Guo, Shimeng
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2020/12/21
Bile acid analog
NASH
TGR5
Cd36
AMPK alpha
TDCPP mimics thyroid hormones associated with the activation of integrin alpha(v)beta(3) and ERK1/2
期刊论文
CHEMOSPHERE, 2020, 卷号: 256, 页码: 1-9
作者:
Li, Jian
;
Liu, Hedan
;
Li, Na
;
Wang, Jinsheng
;
Song, Liuting
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/09/15
TDCPP
BDCPP
Thyroid disruption
Integrin alpha(v)beta(3)
ERK1/2
NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest
期刊论文
NUCLEIC ACIDS RESEARCH, 2020, 卷号: 48, 期号: 16, 页码: 9109-9123
作者:
Sun, Xiaohui
;
Wang, Yan
;
Ji, Kaihua
;
Liu, Yang
;
Kong, Yangyang
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/15
Emerging roles of class I PI3K inhibitors in modulating tumor microenvironment and immunity
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Pu
;
Meng, Ling-hua
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/12/21
phosphoinositide 3-kinase (PI3K)
PI3K inhibitors
tumor microenvironment
immune cells
immunotherapy
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