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浏览/检索结果: 共5条，第1-5条 帮助 限定条件 发表日期：2020    内容类型：期刊论文     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Evaluation of the Estrogenic/Antiestrogenic Activities of Perfluoroalkyl Substances and Their Interactions with the Human Estrogen Receptor by Combining In Vitro Assays and In Silico Modeling 期刊论文 ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 22, 页码: 14514-14524 作者:  Li, Juan;  Cao, Huiming;  Feng, Hongru;  Xue, Qiao;  Zhang, Aiqian 收藏  |  浏览/下载：26/0  |  提交时间：2021/09/14 Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11 作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24 In silico screening  Drug design  CBP  Bromodomain  Inhibitor  Acute Myeloblastic Leukemia   Mechanistic in silico modeling of bisphenols to predict estrogen and glucocorticoid disrupting potentials 期刊论文 SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 728, 页码: 1-11 作者:  Chen, Qinchang;  Zhou, Chengzhuo;  Shi, Wei;  Wang, Xiaoxiang;  Xia, Pu 收藏  |  浏览/下载：21/0  |  提交时间：2021/09/14 Endocrine disruptor  Estrogen receptor  Glucocorticoid receptor  Coregulators  Accelerated molecular dynamics simulations  Binding free energy   A molecular switch regulating transcriptional repression and activation of PPAR gamma 期刊论文 NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 14 作者:  Shang, Jinsai;  Mosure, Sarah A.;  Zheng, Jie;  Brust, Richard;  Bass, Jared 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24 Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292 作者:  Zhang, Feng-cai;  Sun, Zhong-ya;  Liao, Li-ping;  Zuo, Yu;  Zhang, Dan 收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01 CBP bromodomain  small-molecule inhibitor  high-throughput screening  TR-FRET  molecular modeling  human leukemia MV4-11 cells