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科研机构
山东大学 [3]
上海药物研究所 [2]
湖南大学 [2]
武汉大学 [1]
复旦大学上海医学院 [1]
湖南中医药大学 [1]
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期刊论文 [12]
发表日期
2019 [12]
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Research Progress in Tumor Therapy Targeting Plasminogen Activator Inhibitor-1
期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2019, 卷号: 46, 期号: 7, 页码: 663-672
作者:
Liu Ji-Hao
;
Tang Shu-Zhi
;
Hu Li-Hong
;
Huang Ming-Dong
;
Chen Zhuo
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
tumor therapy
plasminogen activator inhibitor-1
tumor microenvironment
Cathepsin K Knockout Exacerbates Haemorrhagic Transformation Induced by Recombinant Tissue Plasminogen Activator After Focal Cerebral Ischaemia in Mice
期刊论文
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2019, 卷号: 39, 期号: 6
作者:
Zhao, Rong
;
He, Xin-Wei
;
Shi, Yan-Hui
;
Liu, Yi-Sheng
;
Liu, Feng-Di
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/12/05
Cathepsin K
Haemorrhagic transformation
Ischaemic stroke
Akt
mTOR
VEGF
tPA Point Mutation at Autolysis Loop Enhances Resistance to PAI-1 Inhibition and Catalytic Activity
期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 页码: 77-86
作者:
Peng, Shuangzhou
;
Xue, Guangpu
;
Chen, Shanli
;
Chen, Zhuo
;
Yuan, Cai
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/11/21
thrombolysis
stroke
tissue-type plasminogen activator
bioengineering
PAI-1 resistance
Tissue Plasminogen Activator Causes Brain Microvascular Endothelial Cell Injury After Oxygen Glucose Deprivation by Inhibiting Sonic Hedgehog Signaling
期刊论文
NEUROCHEMICAL RESEARCH, 2019, 卷号: 44, 期号: 2
作者:
Gong, Pian
;
Li, Mingchang
;
Zou, Changlin
;
Tian, Qi
;
Xu, Zhou
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
Tissue plasminogen activator
Sonic hedgehog signaling pathway
Brain microvascular endothelial cells
Oxygen and glucose deprivation
Blood-brain barrier
Evaluation the combined diagnostic value of TAT, PIC, tPAIC, and sTM in disseminated intravascular coagulation: A multi-center prospective observational study
期刊论文
THROMBOSIS RESEARCH, 2019, 卷号: 173, 页码: 20-26
作者:
Mei, Heng
;
Jiang, Ying
;
Luo, Lili
;
Huang, Ruibin
;
Su, Lei
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/11
Disseminated intravascular coagulation
Thrombin-antithrombin complex
alpha 2-plasmin inhibitor-plasmin complex
Soluble thrombomodulin
Tissue plasminogen activator-inhibitor complex
Efficacy of low molecular weight heparin in spinal trauma patients after part concentrated screw surgery and its influence on blood parameters and the incidence of deep venous thrombosis
期刊论文
Medical Hypotheses, 2019, 卷号: 132
作者:
Shiqing W.
;
Shengzhong M.
;
Cheng Z.
;
Guangqing C.
;
Chunzheng G.
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
Endothelin
Low molecular weight heparin
Part concentrated screw
Pedicle screw surgery
Tissue plasminogen activator
An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy
期刊论文
Journal of Controlled Release, 2019, 卷号: Vol.300, 页码: 1-12
作者:
Yu Huang
;
Li Yu
;
Jie Ren
;
Boram Gu
;
Colin Longstaff
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/17
Activated platelet
Liposome
Tissue plasminogen activator
GPIIb-IIIa integrin
Targeted delivery
Controlled release mechanism
Thrombolysis
An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy.
期刊论文
Journal of controlled release : official journal of the Controlled Release Society, 2019
作者:
Yu Huang
;
Li Yu
;
Jie Ren
;
Boram Gu
;
Colin Longstaff
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
Activated platelet
Controlled release mechanism
GPIIb-IIIa integrin
Liposome
Targeted delivery
Thrombolysis
Tissue plasminogen activator
Effects of thrombolysis within 6 hours on acute cerebral infarction in an improved rat embolic middle cerebral artery occlusion model for ischaemic stroke
期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 4, 页码: 2468-2474
作者:
Si, Zhihua
;
Liu, Jinzhi
;
Hu, Ke
;
Lin, Yan
;
Liu, Jie
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/11
cerebral infarction
recombinant tissue plasminogen activator
stroke
thrombolysis
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation
期刊论文
2019, 卷号: 212, 页码: 36-53
作者:
Ai Q D
;
Chen Chen
;
Chu Shifeng
;
Zhang Zhao
;
Luo Yun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain
BCA = bicinchoninic acid
BSA = bovine serum albumin
CCA = common carotid artery
CCR4 = C-C chemokine receptor type 4
CKLF1 = chemokine-like factor 1
CO-IP = coimmunoprecipitation
ECA = external carotid artery
ELISA = enzyme-linked immunosorbent assay
FDA = Food and Drug Administration
I/R = ischemic/reperfusion
ICA = internal carotid artery
IL-18 = interleukin 18
IL-1β = interleukin 1β
LDH = lactate dehydrogenase
NLRP3 = NOD-like receptor protein 3
PBS = phosphate-buffered saline
SD = standard deviation
TNF-α = tumor necrosis factor α
TTC = 2
3
5-triphenyltetrazolium-chloride
WT = wild-type
pMCAO = permanent middle cerebral artery occlusion
pro-Caspase-1 = precursor Caspase-1
qPCR = quantitative real-time PCR
tMCAO = transient middle cerebral artery occlusion
tPA = tissue plasminogen activator
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