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Research Progress in Tumor Therapy Targeting Plasminogen Activator Inhibitor-1 期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2019, 卷号: 46, 期号: 7, 页码: 663-672
作者:  Liu Ji-Hao;  Tang Shu-Zhi;  Hu Li-Hong;  Huang Ming-Dong;  Chen Zhuo
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/01
Cathepsin K Knockout Exacerbates Haemorrhagic Transformation Induced by Recombinant Tissue Plasminogen Activator After Focal Cerebral Ischaemia in Mice 期刊论文
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2019, 卷号: 39, 期号: 6
作者:  Zhao, Rong;  He, Xin-Wei;  Shi, Yan-Hui;  Liu, Yi-Sheng;  Liu, Feng-Di
收藏  |  浏览/下载:49/0  |  提交时间:2019/12/05
tPA Point Mutation at Autolysis Loop Enhances Resistance to PAI-1 Inhibition and Catalytic Activity 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 页码: 77-86
作者:  Peng, Shuangzhou;  Xue, Guangpu;  Chen, Shanli;  Chen, Zhuo;  Yuan, Cai
收藏  |  浏览/下载:18/0  |  提交时间:2019/11/21
Tissue Plasminogen Activator Causes Brain Microvascular Endothelial Cell Injury After Oxygen Glucose Deprivation by Inhibiting Sonic Hedgehog Signaling 期刊论文
NEUROCHEMICAL RESEARCH, 2019, 卷号: 44, 期号: 2
作者:  Gong, Pian;  Li, Mingchang;  Zou, Changlin;  Tian, Qi;  Xu, Zhou
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/05
Evaluation the combined diagnostic value of TAT, PIC, tPAIC, and sTM in disseminated intravascular coagulation: A multi-center prospective observational study 期刊论文
THROMBOSIS RESEARCH, 2019, 卷号: 173, 页码: 20-26
作者:  Mei, Heng;  Jiang, Ying;  Luo, Lili;  Huang, Ruibin;  Su, Lei
收藏  |  浏览/下载:18/0  |  提交时间:2019/12/11
Efficacy of low molecular weight heparin in spinal trauma patients after part concentrated screw surgery and its influence on blood parameters and the incidence of deep venous thrombosis 期刊论文
Medical Hypotheses, 2019, 卷号: 132
作者:  Shiqing W.;  Shengzhong M.;  Cheng Z.;  Guangqing C.;  Chunzheng G.
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/11
An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy 期刊论文
Journal of Controlled Release, 2019, 卷号: Vol.300, 页码: 1-12
作者:  Yu Huang;  Li Yu;  Jie Ren;  Boram Gu;  Colin Longstaff
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/17
An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy. 期刊论文
Journal of controlled release : official journal of the Controlled Release Society, 2019
作者:  Yu Huang;  Li Yu;  Jie Ren;  Boram Gu;  Colin Longstaff
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/17
Effects of thrombolysis within 6 hours on acute cerebral infarction in an improved rat embolic middle cerebral artery occlusion model for ischaemic stroke 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 4, 页码: 2468-2474
作者:  Si, Zhihua;  Liu, Jinzhi;  Hu, Ke;  Lin, Yan;  Liu, Jie
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/11
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation 期刊论文
2019, 卷号: 212, 页码: 36-53
作者:  Ai Q D;  Chen Chen;  Chu Shifeng;  Zhang Zhao;  Luo Yun
收藏  |  浏览/下载:26/0  |  提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain  BCA = bicinchoninic acid  BSA = bovine serum albumin  CCA = common carotid artery  CCR4 = C-C chemokine receptor type 4  CKLF1 = chemokine-like factor 1  CO-IP = coimmunoprecipitation  ECA = external carotid artery  ELISA = enzyme-linked immunosorbent assay  FDA = Food and Drug Administration  I/R = ischemic/reperfusion  ICA = internal carotid artery  IL-18 = interleukin 18  IL-1β = interleukin 1β  LDH = lactate dehydrogenase  NLRP3 = NOD-like receptor protein 3  PBS = phosphate-buffered saline  SD = standard deviation  TNF-α = tumor necrosis factor α  TTC = 2  3  5-triphenyltetrazolium-chloride  WT = wild-type  pMCAO = permanent middle cerebral artery occlusion  pro-Caspase-1 = precursor Caspase-1  qPCR = quantitative real-time PCR  tMCAO = transient middle cerebral artery occlusion  tPA = tissue plasminogen activator  


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