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科研机构
大连理工大学 [2]
大连化学物理研究所 [2]
湖南大学 [2]
上海中医药大学 [1]
内容类型
期刊论文 [7]
发表日期
2019 [7]
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Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
作者:
Ma, Hong-Ping
;
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2019/06/20
bufotalin
cytochrome P450 3A (CYP3A)
hydroxylation
human liver microsomes (HLMs)
docking simulations
Cytochrome p450 3a enzymes are key contributors for hepatic metabolism of bufotalin, a natural constitute in chinese medicine chansu
期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 10
作者:
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
;
Zhang, Feng
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/05/08
Bufotalin
Cytochrome p450 3a (cyp3a)
Hydroxylation
Human liver microsomes (hlms)
Docking simulations
Inhibition of human cytochrome P450 2A6 by 7-hydroxycoumarin analogues: Analysis of the structure-activity relationship and isoform selectivity
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 136
作者:
Qi, Xiaoyi
;
Dou, Tongyi
;
Wang, Zhongqiong
;
Wu, Jianming
;
Yang, Ling
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/05
CYP2A6
Inhibitor
7-Hydroxycoumarin
Structure-activity relationship
Isoform
Selectivity
Inhibition of human cytochrome P450 2A6 by 7-hydroxycoumarin analogues: Analysis of the structure-activity relationship and isoform selectivity
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 136, 页码: 104944
作者:
Qi, Xiaoyi
;
Dou, Tongyi
;
Wang, Zhongqiong
;
Wu, Jianming
;
Yang, Ling
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/02
CYP2A6
Inhibitor
7-Hydroxycoumarin
Structure-activity relationship
Isoform
Selectivity
Glucuronidation of d-Luciferin In Vitro: Isoform Selectivity and Kinetics Characterization
期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2019, 卷号: 44, 页码: 549-556
作者:
Xia, Yangliu
;
Pang, Huilin
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  |  
浏览/下载:10/0
  |  
提交时间:2019/12/02
Design, synthesis and biological evaluation of novel human monoamine oxidase B inhibitors based on a fragment in an X-ray crystal structure.
期刊论文
Bioorganic & medicinal chemistry letters, 2019
作者:
Kai Cheng
;
Shiyu Li
;
Xiao Lv
;
Yongbin Tian
;
Haiyan Kong
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/12/13
Fragment-based drug design
Isatin
Isoform selectivity
Structure activity relationship
hMAO-B
Design, synthesis and biological evaluation of novel human monoamine oxidase B inhibitors based on a fragment in an X-ray crystal structure
期刊论文
Bioorganic & Medicinal Chemistry Letters, 2019
作者:
Kai Cheng
;
Shiyu Li
;
Xiao Lv
;
Yongbin Tian
;
Haiyan Kong
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/17
hMAO-B
isatin
isoform
selectivity
fragment-based
drug
design
structure
activity
relationship
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