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Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:  Wu, Chenglin;  Xi, Cong;  Tong, Junhua;  Zhao, Jing;  Jiang, Hualiang
收藏  |  浏览/下载:46/0  |  提交时间:2020/07/01
Short-chain chlorinated paraffins (SCCPs) disrupt hepatic fatty acid metabolism in liver of male rat via interacting with peroxisome proliferator-activated receptor a (PPAR alpha) 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 181, 页码: 164-171
作者:  Gong, Yufeng;  Zhang, Haijun;  Geng, Ningbo;  Ren, Xiaoqian;  Giesy, John P.
收藏  |  浏览/下载:97/0  |  提交时间:2019/12/02
Responses of pro- and anti-inflammatory cytokines in zebrafish liver exposed to sublethal doses of Aphanizomenon flosaquae DC-1 aphantoxins 期刊论文
AQUATIC TOXICOLOGY, 2019, 卷号: 215, 期号: 1, 页码: 11
作者:  Zhang, Di;  Tang, Jing;  Zhang, Jing;  Zhang, De Lu;  Hu, Chun Xiang
收藏  |  浏览/下载:170/0  |  提交时间:2019/11/29
Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2019, 期号: 10, 页码: 1396-1411
作者:  Xie, Cen;  Takahashi, Shogo;  Brocker, Chad N.;  He, Shijun;  Chen, Li
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/01
(5R)-5-hydroxytriptolide ameliorates liver lipid accumulation by suppressing lipid synthesis and promoting lipid oxidation in mice 期刊论文
LIFE SCIENCES, 2019, 卷号: 232, 页码: 9
作者:  Dong, Yunxia;  Lu, Henglei;  Li, Qiang;  Qi, Xinming;  Li, Yuanchao
收藏  |  浏览/下载:23/0  |  提交时间:2020/07/01
Modelling liver cancer initiation with organoids derived from directly reprogrammed human hepatocytes 期刊论文
NATURE CELL BIOLOGY, 2019, 卷号: 21, 期号: 8, 页码: 1015-+
作者:  Sun, Lulu;  Wang, Yuqing;  Cen, Jin;  Ma, Xiaolong;  Cui, Lei
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/01
Establishment of a human embryonic stem cell-based liver differentiation model for hepatotoxicity evaluations 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 174, 页码: 353-362
作者:  Liang, Shengxian;  Liang, Shaojun;  Yin, Nuoya;  Faiola, Francesco
收藏  |  浏览/下载:9/0  |  提交时间:2020/10/21
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi
收藏  |  浏览/下载:65/0  |  提交时间:2019/07/29
Myclobutanil accumulation, transcriptional alteration, and tissue injury in lizards (Eremias argus) treated with myclobutanil enantiomers 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 171, 页码: 247-255
作者:  Hao, Weiyu;  Zhang, Yanfeng;  Xie, Yun;  Guo, Baoyuan;  Chang, Jing
收藏  |  浏览/下载:9/0  |  提交时间:2020/10/23
Distribution, metabolism and hepatotoxicity of neonicotinoids in small farmland lizard and their effects on GH/IGF axis 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 662, 页码: 834-841
作者:  Wang, Yinghuan;  Zhang, Yang;  Li, Wei;  Yang, Lu;  Guo, Baoyuan
收藏  |  浏览/下载:14/0  |  提交时间:2020/10/23


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