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Targeting epigenetic machinery: Emerging novel allosteric inhibitors 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2019, 卷号: 204, 页码: 24
作者:  Ye, Fei;  Huang, Jing;  Wang, Hongbo;  Luo, Cheng;  Zhao, Kehao
收藏  |  浏览/下载:21/0  |  提交时间:2020/07/01
Design, synthesis, and biological evaluation of a new class of histone acetyltransferase p300 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 171-190
作者:  Liu, Ruiqi;  Zhang, Zhuqing;  Yang, Hong;  Zhou, Kaixin;  Geng, Meiyu
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/01
DNA methylation modifier LSH inhibits p53 ubiquitination and transactivates p53 to promote lipid metabolism 期刊论文
EPIGENETICS & CHROMATIN, 2019, 卷号: 12, 期号: 1, 页码: 22
作者:  Chen, Ling;  Shi, Ying;  Liu, Na;  Wang, Zuli;  Yang, Rui
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/01
LSH  P53  DUB  PKM2  Lipid metabolism  
Inhibition of G9a by a small molecule inhibitor, UNC0642, induces apoptosis of human bladder cancer cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 8, 页码: 1076-1084
作者:  Cao, Yue-peng;  Sun, Jing-ya;  Li, Mei-qian;  Dong, Yu;  Zhang, Yuan-heng
收藏  |  浏览/下载:17/0  |  提交时间:2020/07/01
SIRT5 Regulates Brown Adipocyte Differentiation and Browning of Subcutaneous White Adipose Tissue 期刊论文
DIABETES, 2019, 卷号: 68, 期号: 7, 页码: 1449-1461
作者:  Shuai, Lin;  Zhang, Li-Na;  Li, Bo-Han;  Tang, Chun-Lan;  Wu, Ling-Yan
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/01
Phosphorylation of TET2 by AMPK is indispensable in myogenic differentiation 期刊论文
EPIGENETICS & CHROMATIN, 2019, 卷号: 12, 页码: -
作者:  Zhang, Ting;  Guan, Xiaowen;  Choi, Un Lam;  Dong, Qiang;  Lam, Melody M. T.
收藏  |  浏览/下载:26/0  |  提交时间:2020/10/21
Stella protein facilitates DNA demethylation by disrupting the chromatin association of the RING finger-type E3 ubiquitin ligase UHRF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 22, 页码: 8907-8917
作者:  Du, Wenlong;  Dong, Qiang;  Zhang, Zhuqiang;  Liu, Baodong;  Zhou, Ting
收藏  |  浏览/下载:18/0  |  提交时间:2020/10/21
The proinflammatory cytokine TNF induces DNA demethylation-dependent and -independent activation of interleukin-32 expression 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 17, 页码: 6785-6795
作者:  Zhao, Zuodong;  Lan, Mengying;  Li, Jingjing;  Dong, Qiang;  Li, Xiang
收藏  |  浏览/下载:6/0  |  提交时间:2020/10/21
Differences in Sensitivity to Environment Depending on Catechol-O-Methyltransferase (COMT) Gene? A Meta-analysis of Child and Adolescent Gene-by-Environment Studies 期刊论文
JOURNAL OF YOUTH AND ADOLESCENCE, 2019, 卷号: 48, 期号: 4, 页码: 655-667
作者:  Cao, Cong;  Cao, Lili;  Chen, Jie
收藏  |  浏览/下载:65/0  |  提交时间:2019/04/22
Discovery of Novel PRMT5 Inhibitors by Virtual Screening and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2019, 卷号: 67, 期号: 4, 页码: 382-388
作者:  Tao, Hongrui;  Yan, Xue;  Zhu, Kongkai;  Zhang, Hua
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/01


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