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上海药物研究所 [18]
生态环境研究中心 [18]
大连化学物理研究所 [15]
湖南大学 [7]
武汉物理与数学研究所 [6]
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期刊论文 [109]
学位论文 [2]
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2019 [111]
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Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:
Hou, Tingjun
;
Li, Dan
;
Chang, Shan
;
Xu, Lei
;
Sun, Huiyong
收藏
  |  
浏览/下载:267/0
  |  
提交时间:2019/06/24
Androgen receptor
AR ligand
Virtual screening
AR agonist
AR antagonist
Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists
期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
作者:
Pan, Chenling
;
Meng, Hao
;
Zhang, Shuqun
;
Zuo, Zhili
;
Shen, Yuehai
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/03/18
delta opioid receptor agonists
3D-QSAR
Homology modeling
Molecular dynamics simulation
Molecular docking
A minimalist peptide ligand for IgG by minimizing the binding domain of protein A
期刊论文
BIOCHEMICAL ENGINEERING JOURNAL, 2019, 卷号: 151, 页码: 8
作者:
Wang, Weiying
;
Hao, Dongxia
;
Ge, Jia
;
Zhao, Lan
;
Huang, Yongdong
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/05/06
Affinity Purification Chromatography
Minimalist Peptide
Protein a
Igg
Rational Design
An aptamer assay for aflatoxin B1 detection using Mg2+ mediated free zone capillary electrophoresis coupled with laser induced fluorescence
期刊论文
TALANTA, 2019, 卷号: 204, 页码: 182-188
作者:
Sun, Linlin
;
Li, Yapiao
;
Wang, Hailin
;
Zhao, Qiang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/09/10
Aptamer
Capillary electrophoresis
Aflatoxin B1
Separation
Affinity binding
Sensor
Estrogen-related receptor gamma is a novel target for Lower-Chlorinated Polychlorinated Biphenyls and their hydroxylated and sulfated metabolites
期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: 254, 页码: -
作者:
Cao, Lin-Ying
;
Ren, Xiao-Min
;
Guo, Liang-Hong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/09/10
Lower-chlorinated PCBs (LC-PCBs)
OH-PCBs
PCB sulfates
Estrogen-related receptor gamma (ERR gamma)
Endocrine disruption effect
Triple functional small-molecule-protein conjugate mediated optical biosensor for quantification of estrogenic activities in water samples
期刊论文
ENVIRONMENT INTERNATIONAL, 2019, 卷号: 132, 页码: -
作者:
Liu, Lanhua
;
Zhou, Xiaohong
;
Lu, Yun
;
Shi, Hanchang
;
Ma, Mei
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/10/23
Estrogen receptor
Small-molecule-protein conjugate
Optical fiber biosensor
17 beta-estradiol equivalent concentration
Wastewater sample
Unique N-glycosylation of a recombinant exo-inulinase from Kluyveromyces cicerisporus and its effect on enzymatic activity and thermostability
期刊论文
Journal of Biological Engineering, 2019, 卷号: 13, 期号: 1
作者:
Ma,Junyan
;
Li,Qian
;
Tan,Haidong
;
Jiang,Hao
;
Li,Kuikui
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  |  
浏览/下载:277/0
  |  
提交时间:2019/12/02
N-glycosylation
Exo-inulinase
β-Sandwich domain
Enzyme activity
Thermostability
Two validated liquid chromatography-mass spectrometry methods with different pretreatments for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum compared with an electrochemiluminescence method
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 175, 页码: 11
作者:
Gao, Yuxiong
;
Zhang, Dan
;
Yang, Changyong
;
Duan, Xiaotao
;
Li, Xiuli
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Anti-CD47 monoclonal antibody
LC-MS
Adsorption issue
Electrochemiluminescence
Pharmacokinetics
Cross-validation
Peptide Nanotube-Templated Biomineralization of Cu2-xS Nanoparticles for Combination Treatment of Metastatic Tumor
期刊论文
SMALL, 2019, 页码: 13
作者:
Lai, Yi
;
Xu, Zhiai
;
Hu, Xianli
;
Lei, Li
;
Li, Lingling
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
biomineralization
cancer metastasis
combination therapy
Fenton reaction
peptide nanotubes
Short-chain chlorinated paraffins (SCCPs) disrupt hepatic fatty acid metabolism in liver of male rat via interacting with peroxisome proliferator-activated receptor a (PPAR alpha)
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 181, 页码: 164-171
作者:
Gong, Yufeng
;
Zhang, Haijun
;
Geng, Ningbo
;
Ren, Xiaoqian
;
Giesy, John P.
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2019/12/02
SCCPs
Mode of action
PPAR alpha
Luciferase assay
Molecular docking
Metabolomics
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