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科研机构
上海药物研究所 [131]
内容类型
期刊论文 [131]
发表日期
2019 [131]
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共131条,第1-10条
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发表日期:2019
专题:上海药物研究所
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Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:
Xiao, Li
;
Wang, Yujun
;
Zhang, Mumei
;
Wu, Weiwei
;
Kong, Linghui
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2020/07/01
DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15
作者:
Zhang, Zongwang
;
Wu, Yanwei
;
Wu, Bing
;
Qi, Qing
;
Li, Heng
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Systemic sclerosis
SAHH inhibitor
Fibrosis
Inflammation
Vasculopathy
TGF-beta
alpha-Mangostin remodels visceral adipose tissue inflammation to ameliorate age-related metabolic disorders in mice
期刊论文
AGING-US, 2019, 卷号: 11, 期号: 23, 页码: 11084-11110
作者:
Li, Dan
;
Liu, Qianyu
;
Lu, Xiuqiang
;
Li, Zhengqiu
;
Wang, Chunming
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
alpha-mangostin
aging
adiposity
adipose tissue inflammation
macrophage
Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease
期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14
作者:
Zhang, Yu
;
Wu, Qimei
;
Zhang, Lei
;
Wang, Qing
;
Yang, Zexian
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Caffeic acid
A53T
Parkinson's disease
Autophagy
JNK
Discovery of a novel protein kinase C activator from Croton tiglium for inhibition of non-small cell lung cancer
期刊论文
PHYTOMEDICINE, 2019, 卷号: 65, 页码: 11
作者:
Wang Yuwei
;
Tang Chunping
;
Yao Sheng
;
Lai Huanling
;
Li Runze
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
Natural product
Croton tiglium
Protein kinase C
Molecular modelling
Metabolic Evaluation of MYCN-Amplified Neuroblastoma by 4-[F-18]FGln PET Imaging
期刊论文
MOLECULAR IMAGING AND BIOLOGY, 2019, 卷号: 21, 期号: 6, 页码: 1117-1126
作者:
Li, Chao
;
Huang, Shuo
;
Guo, Jun
;
Wang, Cheng
;
Huang, Zhichao
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Glutamine
PET
MYCN
ASCT2
Neuroblastoma
Enantiomeric pairs of meroterpenoids from Rhododendron fastigiatum
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 963-969
作者:
Huang Guang-Hui
;
Lei Chun
;
Zhu Ke-Xin
;
Li Jing-Ya
;
Li Jia
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Rhododendron fastigiatum
Meroterpenoid enantiomers
Protein tyrosine phosphatase 1B
Synthesis of Aryl Propionamide Scaffold Containing a Pentafluorosulfanyl Moiety as SARMs
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 23, 页码: 13
作者:
Shao, Pingxuan
;
Zhou, Yan
;
Yang, Dehua
;
Wang, Ming-Wei
;
Lu, Wei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/07/01
pentafluorosulfanyl
aryl propionamide
androgen receptor
agonist
SARMs
Effects of traditional Chinese medicine formula Le-Cao-Shi on hepatitis B: In vivo and in vitro studies
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 244, 页码: 10
作者:
Zhao, Qing
;
Ren, Xia
;
Chen, Min
;
Yue, Shi-Jun
;
Zhang, Meng-Qi
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
Traditional Chinese medicine
Formula Le-Cao-Shi
Hepatitis B virus
Anti-Hepatitis B
Genetically Encoded Residue-Selective Photo-Crosslinker to Capture Protein-Protein Interactions in Living Cells
期刊论文
CHEM, 2019, 卷号: 5, 期号: 11, 页码: 2955-2968
作者:
Hu, Wei
;
Yuan, Yi
;
Wang, Cai-Hu
;
Tian, Hong-Tao
;
Guo, An-Di
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
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