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科研机构
上海药物研究所 [31]
内容类型
期刊论文 [31]
发表日期
2019 [31]
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共31条,第1-10条
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发表日期:2019
专题:上海药物研究所
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Pao Pereira Extract Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by inhibiting 5 alpha-Reductase
期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 10
作者:
Liu, Jiakuan
;
Fang, Tian
;
Li, Meiqian
;
Song, Yuting
;
Li, Junzun
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
Imaging Tumorous Methylglyoxal by an Activatable Near-Infrared Fluorescent Probe for Monitoring Glyoxalase 1 Activity
期刊论文
ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 期号: 24, 页码: 15577-15584
作者:
Ding, Chunyong
;
Wang, Fengyang
;
Dang, Yijing
;
Xu, Zhiai
;
Li, Lingling
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Neuroprotective Effect of Natural Alkaloid Fangchinoline Against Oxidative Glutamate Toxicity: Involvement of Keap1-Nrf2 Axis Regulation
期刊论文
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2019, 卷号: 39, 期号: 8, 页码: 1177-1186
作者:
Bao, Fengxia
;
Tao, Lingxue
;
Zhang, Haiyan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Fangchinoline
Keap1
Nrf2
Oxidative stress
USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells
期刊论文
CANCER MEDICINE, 2019, 卷号: 8, 期号: 15, 页码: 6730-6740
作者:
Lu, Qin
;
Zhang, Fang-Lin
;
Lu, Da-Yun
;
Shao, Zhi-Ming
;
Li, Da-Qiang
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
BRCA1
breast cancer
deubiquitinase
PARP inhibitor
USP9X
Lycodine-type alkaloids from Lycopodiastrum casuarinoides and their acetylcholinesterase inhibitory activity
期刊论文
FITOTERAPIA, 2019, 卷号: 139, 页码: 7
作者:
Feng, Zheling
;
Chen, Shixin
;
Wang, Wei
;
Feng, Lu
;
Dong, Yanyan
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Lycopodiastrum casuarinoides
Lycopodiaceae
Lycodine-type alkaloids
TD-DFT
ECD
Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 398-416
作者:
Wang, Yibing
;
Lou, Yang
;
Wang, Jiang
;
Li, Dan
;
Chen, Hui
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
SGLT2 inhibitors
Diabetes
Sugar modification
Structure-activity relationship
Urinary glucose excretion
Oral glucose tolerance
DNA methylation modifier LSH inhibits p53 ubiquitination and transactivates p53 to promote lipid metabolism
期刊论文
EPIGENETICS & CHROMATIN, 2019, 卷号: 12, 期号: 1, 页码: 22
作者:
Chen, Ling
;
Shi, Ying
;
Liu, Na
;
Wang, Zuli
;
Yang, Rui
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
LSH
P53
DUB
PKM2
Lipid metabolism
NLG919/cyclodextrin complexation and anti-cancer therapeutic benefit as a potential immunotherapy in combination with paclitaxel
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 138, 页码: 8
作者:
Xu, Jian
;
Ren, Xiaohong
;
Guo, Tao
;
Sun, Xian
;
Chen, Xiaojin
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
Cyclodextrins
NLG919
Solubility enhancement
Paclitaxel
IDO-1 combination immunochemotherapy
Design of wogonin-inspired selective cyclin-dependent kinase 9 (CDK9) inhibitors with potent in vitro and in vivo antitumor activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178, 页码: 782-801
作者:
Wang, Jubo
;
Li, Tinghan
;
Zhao, Tengteng
;
Wu, Tizhi
;
Liu, Chuang
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Wogonin
CDK9
AML
Flavonoid
Antitumor
SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met
期刊论文
CANCER SCIENCE, 2019, 页码: 11
作者:
Tong, Mengya
;
Gao, Mingzhao
;
Xu, Yongping
;
Fu, Li
;
Li, Yun
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
AZD9291
c-Met ADC
c-Met overexpression
resistance
SHR-A1403
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