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科研机构
上海药物研究所 [10]
内容类型
期刊论文 [10]
发表日期
2019 [10]
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发表日期:2019
专题:上海药物研究所
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Two validated liquid chromatography-mass spectrometry methods with different pretreatments for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum compared with an electrochemiluminescence method
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 175, 页码: 11
作者:
Gao, Yuxiong
;
Zhang, Dan
;
Yang, Changyong
;
Duan, Xiaotao
;
Li, Xiuli
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Anti-CD47 monoclonal antibody
LC-MS
Adsorption issue
Electrochemiluminescence
Pharmacokinetics
Cross-validation
Intravenous formulation of Panax notoginseng root extract: human pharmacokinetics of ginsenosides and potential for perpetrating drug interactions
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1351-1363
作者:
Pintusophon, Salisa
;
Niu, Wei
;
Duan, Xiao-na
;
Olaleye, Olajide E.
;
Huang, Yu-hong
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
ginsenoside
cytochrome P450 3A
organic anion-transporting polypeptide 1B3
herbal medicine-drug interactions
XueShuanTong
Panax notoginseng
Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236
作者:
Duan, Zhe
;
Liu, Jingqiu
;
Niu, Liping
;
Wang, Jun
;
Feng, Mingqian
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/07/01
IDH1 mutation
High-throughput screening
Pan-inhibitor
2-HG
Gliomas
Inhibition of MAPK/ERK pathway promotes oligodendrocytes generation and recovery of demyelinating diseases
期刊论文
GLIA, 2019, 卷号: 67, 期号: 7, 页码: 1320-1332
作者:
Suo, Na
;
Guo, Yu-e
;
He, Bingqing
;
Gu, Haifeng
;
Xie, Xin
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
differentiation
ERK
MAPK
MEK inhibitor
myelin
oligodendrocyte
oligodendrocyte progenitor cell
remyelination
Pyrrole-Hemoglobin Adducts, a More Feasible Potential Biomarker of Pyrrolizidine Alkaloid Exposure
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 6, 页码: 1027-1039
作者:
Ma, Jiang
;
Ruan, Jianqing
;
Chen, Xinmeng
;
Li, Dongping
;
Yao, Sheng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis
期刊论文
Toxicology and applied pharmacology, 2019, 卷号: 363, 页码: 142-153
作者:
Wang, Anqi
;
Zhou, Fayang
;
Li, Dan
;
Lu, Jin-Jian
;
Wang, Yitao
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
gamma-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 363, 页码: 142-153
作者:
Wang, Anqi
;
Zhou, Fayang
;
Li, Dan
;
Lu, Jin-Jian
;
Wang, Yitao
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/01
gamma-Mangostin
Fibrogenesis
Sirtuin 3
HMGB1
Superoxide
Liver fibrosis
Nano-Structural Effects on Gene Transfection: Large, Botryoid-Shaped Nanoparticles Enhance DNA Delivery via Macropinocytosis and Effective Dissociation
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 6, 页码: 1580-1598
作者:
Zhang, Wenyuan
;
Kang, Xuejia
;
Yuan, Bo
;
Wang, Huiyuan
;
Zhang, Tao
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
gene delivery
PEI
micropinocytosis
TRAIL
local-regional gene therapy
cervical cancer
Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7-ones Derivatives as Covalent L85812/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 8, 页码: 826-834
作者:
Niu, Ao
;
Wang, Yang
;
Yang, Yushe
;
Wei, Jianhai
;
Ding, Jian
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
irreversible inhibitors
EGFR(T79014)( )mutant
anti-tumor
xenograft model
cell proliferation
Roles of Renal Drug Transporter in Drug Disposition and Renal Toxicity
期刊论文
DRUG TRANSPORTERS IN DRUG DISPOSITION, EFFECTS AND TOXICITY, 2019, 卷号: 1141, 页码: 341-360
作者:
Yang, Xinning
;
Han, Li
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
SLC transporters
ABC transporters
Drug disposition
Nephrotoxicity
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